Yttrium microsphere therapy

Yttrium Microsphere Therapy for Unresectable Hepatic Metastases... [Pg.119]

Table 11.2. Modern retrospective studies of yttrium microsphere therapy for liver metastases from colorectal cancers... [Pg.120]

Campbell AM, Bailey IH, Burton MA (2000) Analysis of the distribution of intra-arterial microspheres in human liver following hepatic yttrium-90 microsphere therapy. Phys Med Biol 45 1023-1033... [Pg.10]

Murthy R, Nunez R, Szklaruk J et al (2005) Yttrium-90 microsphere therapy for hepatic malignancy devices, indications, technical considerations, and potential complications. Radiographics 25 Suppl l S41-55... [Pg.14]

Two components relate to the topic of dosimetry in microsphere therapy. Dose (Gy) that is desired to be delivered to tumor tissue in the liver and the activity (GBq) of yttrium-90 ( Y) delivered to the target... [Pg.51]

Sarfaraz M, Kennedy AS, Cao ZJ, Sackett GD, Yu CX, Lodge MA, Murthy R, Line BR, Van Echo DA (2003) Physical aspects of yttrium-90 microsphere therapy for nonresectable hepatic tumors. Med Phys 30 199-203... [Pg.57]

Lau WY, Ho S, Leung TW, Chan M, Ho R, Johnson PJ, Li AK (1998) Selective internal radiation therapy for nonresectable hepatocellular carcinoma with intraarterial infusion of yttrium microspheres. Int J Radiat Oncol Biol Phys 40 583-592... [Pg.90]

Stubbs RS, Cannan RJ, Mitchell AW (2001) Selective internal radiation therapy (SIRT) with Yttrium microspheres for extensive colorectal liver metastases. Hepa-togastroenterology 48 333-337... [Pg.92]

Roberson PL, Ten Haken R, McShan DL et al (1992) Three-dimensional tumor dosimetry for hepatic Yttrium-90 microsphere therapy. J Nuclear Medicine 33 735-738... [Pg.123]

Murthy R, Brown DB, Salem R et al (2007) Gastrointestinal complications associated with hepatic arterial Yttrium-90 microsphere therapy. J Vase Interv Radiol 18 553-561 quiz 562... [Pg.88]

Supplementation of drug therapy using internal radiation by intra-arterial delivery of radiolabeled microspheres Yttrium 90... [Pg.552]

Salem R, Thurston KG, Carr B et al (2002) Yttrium-90 microspheres radiation therapy for unresectable liver cancer. J Vase Interv Radiol 13 S223-229... [Pg.10]

Carr B, Torok F, Sheetz M et al (2002) A novel and safe therapy for advanced-stage hepatocellular carcinoma (HCC) hepatic arterial Yttrium-labeled glass microspheres (TheraSphere). Int J Cancer [Suppl] 13 459... [Pg.10]

Radioembolization with yttrium-90 ( Y) microspheres represents an innovative approach that has gained increasing awareness and clinical use over the past 5-10 years. The minimal toxicity of radioembolization and the ability to discharge the patient on an outpatient basis make the therapy an attractive alternative in the treatment of primary and metastatic liver malignancies. Patients are able to resume normal activities shortly following treatment, with minimal side effects, in contrast to the post-embolization syndrome often associated with current chemoembolic techniques. [Pg.147]

As in the case for transarterial chemoemboliza-tion (FACE, Chapter 10), radioembolization takes advantage of the preferential hepatic arterial supply of hepatocellular carcinoma (HCC) to deliver targeted therapy to the tumor, relatively sparing the liver parenchyma, which is mostly supported by the portal venous system. Radioembolization is effected via intra-arterial delivery of carrier spheres onto which radioactive particles are attached. There are two types of radioactive microspheres that can be used in the treatment of primary (and metastatic for that matter) liver disease. They both contain Yttrium-90 ( °Y) as the active element but differ in the type of carrier particle. The first is Y glass... [Pg.141]

Liu D, Salem R, Bui. JT, Courtney A, Barakat 0, Sergie Z, Atassi B, Barrett K, Lewandowski RJ, Wong CO, Gates VL, Thurston KG Angiographic considerations in patients undergoing liver-directed therapy with yttrium-90 microspheres and chemoembolization a comprehensive review. J Vase Interv Radiol 2005, in press... [Pg.160]

External beam radiation therapy is an alternative treatment for patients with splenomegaly [131-135]. Similarly, transcatheter arterial brachytherapy using yttrium-90 microspheres has been reported... [Pg.215]

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