Workplace exposure, carcinogen risk assessment

Chronic Exposure and Carcinogenicity. A number of studies in animals indicate that inhalation of BCME is associated with risk of nasal or lung tumors. In order to assess the potential risks in the workplace, further studies in animals might be helpful in improving information on the dose and time-dependency of BCME-induced tumorigenesis. In particular, studies would be valuable to investigate why BCME induces tumors with such a short latency, and why it results in nasal tumors in some species and lung tumors in others. Studies on the interaction of BCME with other chemicals such as CME (with which it is often associated in the workplace) would also be valuable. 

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