Workflow components

The 48-channel MCFB reactor and the catalyst synthesis workflow components were similarly validated in experiments where bulk samples were prepared in library format, screened in the array format, and the data compared with known examples. This part of the workflow was used for initial hit validation and to opti-... 

Review and approval of protocols, e.g., within a workflow component... 

An electronic document management system is used for the maintenance of corporate and local standard operating procedures (SOPs). It includes functionality for document control, but also a workflow component for creating drafts, reviewing, approving, and distributing documents and supports electronic signatures... 

In order to execute a combinatorial approach for discovery of novel electrocatalyst materials, several key workflow components need to be in place, including the ability to generate a large mrmber of electrocatalyst powders with variation in the composition and microstructure and to test their activity in the ORR by a rapid screening technique. 

In the last step of the workflow, components can be dynamically loaded into the platform, depending on results of the analysis. If all constraints in the analysis step are satisfied, the system modelled in the first step is consistent, i.e., we say the system configuration is assured. Thus, any change in the modelling step can be captured and analyzed in the constraint network. 

As a suitable model reaction to highlight the steps necessary to successfully translate thermal conditions to microwave conditions, and to outline the general workflow associated with any microwave-assisted reaction sequence, in this section we describe the complete protocol from reaction optimization through to the production of an automated library by sequential microwave-assisted synthesis for the case of the Biginelli three-component dihydropyrimidine condensation (Scheme 5.1) [2, 3],... 

The previous chapters have dealt mainly with LC/MS analysis involving short run times, many samples, and relatively small numbers of compounds in samples. What about samples containing very complex compound mixtures, for example, natural products, samples from biomarker discovery, protein digests, and QA/QC method development or metabolite identification samples requiring detection of every component Such workflows often require several analysis steps with different columns and different mobile phases and pH values to increase the separation probability by changing the selectivities of individual runs. 

For a component to be generic, you must provide ways that your clients designers can specialize it to their needs. The techniques include parameters passed when a function is called tables read by the component configuration or deployment options on the component plug-points—a place where the component can be plugged into a variety of other components and frameworks, such as a workflow system, into which a variety of components can be plugged. 

Components have a richer range of intercommunication mechanisms such as events and workflows, rather than only the basic 00 message. These mechanisms support easier composition of the parts. 

Connectors that support workflow Objects are transferred between one component and the next, where this transfer is itself a significant event. 

A Transfer port passes objects from the source to the sink. Once accepted by the sink, a sent object is no longer in the sender. Strings of components with Transfer ports can be used to make pipelines and workflows. In an implementation, the source asks the sink to accept an object if and when the object is accepted, the source removes it from its own space. 

In this case study we have not adopted any particular component architecture such as Cat One (see Section 10.8.1, Cat One An Example Component Architecture). So our connectors have been limited to standard requests or responses between large-grained components rather than higher-level facilities such as events, properties, and workflow transfers. 

Component technology This includes the kinds of components and connectors that define more-expressive modeling and design constructs such as events, properties, workflow transfers, and replication. 

UML offers one notation to define the interface of a component (the lollipop notation). Catalysis recognizes that component technology is about the connecting together of encapsulated units. The types of these connections will vary a given component architecture will define its own types. You can define a component architecture using frameworks and then use those frameworks to compose components as diverse as workflow, event-property-method connections, and traditional objects. 

The third P in the program is product and describes MED s commitment to developing trend-setting, innovative technologies that drive growth. This approach requires that the company intimately understands customers workflow, e.g. their clinical and operational processes, their process interfaces as well as the interfaces between MED s equipment, IT, and services, and the interaction of all these components. 

Fig. 1.4 compares, in topological format, the space-time yield versus composition for the data presented in the 1978 Union Carbide publication and the activity rankings observed in the SMS in an experiment that took less than 4 h, most of which was unattended. The correlation is remarkable. The primary synthesis and screening components of the workflow were thus validated. Hif criteria were established that involved ranking the yield of the reaction over the various catalysts (the activity figure of merit multiplied by selectivity). The hif criteria performance bar increased as the discovery program evolved and improved systems were discovered. 

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