Volatile organic compounds in breath

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Phillips, M., J. Greenberg, and J. Awad, Metabolic and Environmental Origins of Volatile Organic Compounds in Breath, J. Clin. Pathol., 47, 1052-1053 (1994). 

Raymer JH, Peiiizzari ED, Thomas KW, etal. 1991. Elimination of volatile organic compounds in breath after exposure to occupational and environmental microenvironments. Journal of Exposure Analysis and Environmental Epidemiology 1 439-452. 

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McVay, W. P. Volatile organic compounds in breath as markers of lung cancer a cross-sectional study. Lancet 353, 1930-1933, 1999. 

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Guam, A.V. Carreras, A. Calvo, D. Agudol, L Navajas, D. Pardo, A. Marco, S. Farre, R., Rapid detection of sepsis in rats through volatile organic compounds in breath, J. Chwmatogr. B. Anal. Technol. Biotned. Life Sci. 2012, 881—882, 76-82. 

Reynolds, J.C., Blackburn, G.J., Guallar-Hoyas, C Moll, V.H., Bocos-Bintintan, V., Kaur-Atwal, G., Howdle, M.D., Harry, E.L., Brown, L.J., Creaser, C.S., Thomas, C.L. (2010) Detection of Volatile Organic Compounds in Breath Using Thermal Desorption Electrospray lonization-lon Mobility-Mass Spectrometry. Anal Chem. 82 2139-2144. 

O Hara, M. E., Clutton-Brock, T. H., Green, S., Mayhew, C. A. (2009) Endogenous volatile organic compounds in breath and blood of healthy volunteers examining breath analysis as a surrogate for blood measurements. J. Breath Res. 3,027005. 

Wallace LA, Pellizzari ED, Hartwell TD, et al. 1986a. Total exposure assessment methodology (TEAM) study Personal exposures, indoor-outdoor relationships, and breath levels of volatile organic compounds in New Jersey. Environ Int 12 369-387. 

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Thomas KW, Pellizzari ED, Cooper SD. 1991. Canister based method for collection and GC/MS analysis of volatile organic compounds in human breath. J Anal Toxicol 15 54-59. 

Phillips M, Greenberg J. 1992. Ion-trap detection of volatile organic compounds in alveolar breath. Clin Chem (Winston-Salem, N. C.) 38(l) 60-5. 

Sanchez, J.M., Sacks, R.D. (2006) Development of a multibed sorption trap, comprehensive two-dimensional gas chromatography, and time-of-flight mass spectrometry system for the analysis of volatile organic compounds in human breath. Anal. Chem. 78 3046-3054. 

Wallace LA, Peiiizzari E, Hartwell T, et al. 1986c. Concentrations of 20 volatile organic compounds in the air and drinking water of 350 residents of New Jersey compared with concentrations in their exhaled breath. J Occup Med 28 603-608. 

Phillips M., Herrera J., Krishnan S., Zain M., Greenberg J., and Cataneo R., Variation in volatile organic compounds in the breath of normal humans, J. Chromatogr. Biomed. Appl, 729, 75-88, 1999. 

Another exciting clinic-based use of IMS, as a combined GC-IMS instrument, is the determination of metabolites in human breath. Emphasis was given to sampling VOCs (volatile organic compounds) from breath to aid choices of therapy for respiratory infections, to monitor the course of treatment, and finally to probe for tumors. These efforts have received both acceptance and honors in the medical community in Europe. ... 

Westhoff, M. Litterst, P. Freitag, L. Urfer, W. Bader, S. Baumbach, J.L, Ion mobility spectrometry for the detection of volatile organic compounds in exhaled breath of patients with lung cancer results of a pilot study. Thorax 2009, 64, 744-748. 

Ulanowska, A. Ligor, M. Amaim, A. Buszewski, B., Determination of volatile organic compounds in exhaled breath by ion mobility spectrometry, Chem. Analityczna 2008, 53, 953-965. 

Riter, L.S. Laughlin, B.C. Nikolaev, E.N. Cooks, R.G. Direct analysis of volatile organic compounds in human breath using a miniaturized cylindrical ion trap mass spectrometer with a membrane inlet. Rapid Commun. Mass Spectrom. 2002, 16, 2370-2373. 

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