Vitreous skin sections

Cryo-Transmission Electron Microscopy of Vitreous Skin Sections. 37... 

To better understand the structure, function, and dynamics of the endogenous lipid matrix of the stratum corneum intercellular space some general principles of lipid phase behavior, dynamics, and structural organization may represent a useful starting point. Further follows a short overview of some basic physico-chemical principles that may be of relevance for stratum corneum lipid research, followed by a presentation of the new technique cryo-transmission electron microscopy of fully hydrated vitreous skin sections and how this technique recently has been applied to the study of the structural organization and formation of the lipid matrix of the stratum corneum intercellular space. 

CRYO-TRANSMISSION ELECTRON MICROSCOPY OF VITREOUS SKIN SECTIONS... 

Al-Amoudi, A., Dubochet, J., and Norlen, L.P.O. (2005) Nanostructure of the epidermal extracellular space as observed by cryo-electron microscopy of vitreous sections of human skin. J. Invest. Dermatol. 124 764-777. 

These polyglycans have important and varied psychological roles in animal tissue. Hyaluronic acid, for instance, is known to occur in the dermis of the skin, in the vitreous fluids of the eye, and in the body s synovial fluids (67). It has many functions, the most significant being cellular turgidity (because of its water-binding capacity) and lubrication. It has also been shown to play a key role in wound healing, which will be discussed in Section lll.F.l. 

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