Uterine prolapse

Levormeloxifene osteoporosis phase III, cancelled uterine prolapse (among others)... 

Idoxifene has been evaluated as a breast cancer treatment for postmenopausal patients [296, 297]. In one study, 321 postmenopausal patients with unknown receptor status or hormone receptor-positive metastatic breast cancer were randomized to receive either tamoxifen or idoxifene as first-line endocrine therapy for their advanced disease. Complete plus partial response rates were 9 and 13% for tamoxifen and idoxifene, respectively. The median time to progression was slightly higher for idoxifene (140 versus 166 days), but these differences were not statistically significant. Morbidity was similar for both groups. The authors concluded that in postmenopausal women with metastatic breast cancer idoxifene had similar efficacy and toxicity to tamoxifen [298]. However, idoxifene has not been developed further because of concerns about uterine prolapse [299]. This side-effect is not seen with tamoxifen. 

For uterine prolapse, add Fructus Alpiniae Oxyphyllae (Yi Zhi Ren), Folium Artemisiae Argyii (Ai Ye), and Fructus Schizandrae Chinensis (Wu WeiZi). 

Huang-qi is used in TCM prescriptions for ch i (energy) deficiency and general weaJaiess and specifically for shortness of breath and palpitation, collapse, spontaneous perspiration, night sweats, edema due to physical deficiency, chronic nephritis, pulmonary diseases, lingering diarrhea, rectal and uterine prolapse, nonfestering boils, and hard-to-heal sores and wounds. Immunostimulant, antioxidant, antiviral, and antitumor activities are found. 

Reproductive disorders Endometrial disorder Leukorrhea Uterine disorder Uterovaginal prolapse Vaginal discomfort Urinary system disorders Micturition frequency Urinary incontinence Gastrointestinal disorders Abdominal pain Constipation... 

Intraocular pressure is slightly increased by ketamine. Uterine tone and intrauterine pressure are increased in both the non-pregnant and pregnant uterus, effects that may be harmful in abruptio placentae and cord prolapse. Ketamine rapidly crosses the placenta and equilibrates in fetal plasma. Transient rashes have been reported in 20% of patients although life-threatening reactions are rare. Indications... 

Excessive sweating, severe cough, shortness of breath, asthma, palpitations, uterine bleeding, spermatorrhea, premature ejaculation, large amount of leukorrhea, incontinence of urine, enuresis, diarrhea, prolapse of rectum and uterus. 

Some of these species are B. chinense, B. falcatum, B. gibraltaricum and B. kaoi, often used in combination with other plants as antihepatotoxic, antipyretic, analgesic, sedative, and antidepressive agents, in cases of menstrual complaints, uterine and anal prolapses, sudden loss of hearing and malaria [2-4]. 

The rate of pregnancy induction ranges from 9.5% to 33.5%. The most common reason for induction is postdatism (>42 weeks), which occurs in 10% of all pregnancies. Other reasons for induction include suspected fetal growth retardation, maternal hypertension, premature rupture of membranes with no active onset of labor, or social factors. Contraindications for induction include placenta previa, oblique or transverse lie, pelvic structure abnormality, prolapsed umbilical cord, and active herpes. The concerns associated with induction of labor are that the labor may be ineffective or that side effects such as uterine hyperstimulation may adversely affect the infant, increasing the likelihood of cesarean section. 

Dewan PA (1996) A study of the relationship between syrin-goceles and Cobb s collar. Eur Urol 30 119-124 Dhillon HK, Yeung CK, Duffy PG et al (1993) Cowper s glands cysts-a cause of transient intra-uterine bladder outflow obstruction. Fetal Diagn Ther 8 51-55 Diard F, EklOf O, Lebowitz RL et al (1981) Urethral obstruction in boys caused by prolapse of simple ureterocele. Pediatr Radiol 11 139-142... 

There are two halves of the exstrophied bladder, separated by an exstrophied ileocecal bowel area. On the rostral side of the bowel exstrophy the ileum prolapses. In addition there is imperforate anus, and the colon may be duplicated. Usually a duplicated appendix is found. In males a small, duplicated penis can be seen. In females the vagina is septated and uterine abnormalities are likely. A high proportion of these patients will also present a small to giant omphalocele (Duckett and Cladamone 1985). 

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