Used for Gastrointestinal Tract Disorders

Midazolam Hydrochloride Midazolam hydrochloride is incompatible with a number of drugs, and precipitation is observed, presumably due to a pH of 5 or more with dimenhydrinate, pentobarbitone sodium, perphenazine, frusemide, thiopentone, prochlorperazine edisylate, ranitidine hydrochloride, and various intravenous fluids.164 Solutions of midazolam hydrochloride should not be combined with Hartmann s solution, as the potency of midazolam may be affected.165 

Paraldehyde Care must be exercised when using paraldehyde. It must not be administered if is brownish in color or gives off a sharp odor of acetic acid. Degradation is much more pronounced once the containers are opened. Polypropylene or glass syringes with natural rubber-tipped plastic plungers are acceptable only for the immediate administration or measurement of paraldehyde doses. 

Prochlorperazine Edisylate Prochlorperazine edisylate is not compatible with sodium chloride solutions containing methyl hydroxybenzoate and propyl hydroxy-benzoate as preservatives, but is compatible with solutions containing benzyl alcohol. Prochlorperazine edisylate salts are incompatible with a number of drugs such as aminophylline, amphotericin, ampicillin sodium, some barbiturates, ben-zylpenicillin salts, calcium gluconate, cefmetazole sodium, cephalothin sodium, chloramphenicol sodium succinate, chlorothiazide sodium, chloramphenicol, morphine sulfate containing phenol, magnesium trisilicate mixture, sodium succinate, chlorothiazide sodium, dimenhydrinate, heparin sodium, hydrocortisone sodium succinate, midazolam hydrochloride, and some sulfonamides.166 

Solution of thioridazine hydrochloride is incompatible with carbamazepine suspensions. Cessation of therapy or drug reduction with troopiclone may cause dependence and withdrawal symptoms. Patients taking this drug should avoid operating machinery or industrial work and driving.168 

Care should be taken when administering aluminium salts such as aluminium hydroxide in patients with renal dysfunction and bone diseases. Patients with renal 

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