Typhoid bacillus

The term carrier may also be applied to a person who is infected with a disease organism, but who shows no signs of the disease. Typhoid Mary was a cook in New York City who appeared to be healthy although she carried the typhoid bacillus. An investigation showed that she transmitted typhoid fever to at least 100 other people before it was discovered that she was a carrier. 

Change in final pH at fixation depends largely on the type of enzyme. The final pH of glucosidase shifted to an acidic profile at 0.7 units by fixation on dimethyl-aminated superfine fiber. This is probably due to static repulsion between the proton and the amine groups. However, in the case of invertase or P-galactosidase firom the typhoid bacillus, there was no shift in the final pH. 

Continuous hydrolysis of galactose is attempted by passing galactose solution through the column where aminated fiber, to which P-galactosidase firom the typhoid bacillus is fixed, is packed. After 12 days, there were few problems other than the plugging of the column. During the entire period, the flow rate was nearly constant and there was no sudden decrease in activity. The half-life was approximately one month [13]. 

Currently available live vaccines include measles, mumps, polio, rubella, vaccinia (smallpox), varicella (chickenpox), and yellow fever. All of these are made from viruses. There are two live bacterial vaccines 1) Bacillus of Calmette and Guerin (BCG) vaccine for tuberculosis and 2) oral typhoid. 

A. Characteristics. Tularemia is a zoonotic disease caused by Francisella tularensis, a gramnegative bacillus. Humans acquire the disease under natural conditions through inoculation of skin or mucous membranes with blood or tissue fluids of infected animals, or bites of infected deerflies, mosquitoes, or ticks. Less commonly, inhalation of contaminated dust, or ingestion of contaminated foods or water, may produce clinical disease. A BW attack with F. tularensis delivered by aerosol would primarily cause typhoidal tularemia, a syndrome expected to have a case fatality rate which may be higher than the 5-10% seen when the disease is acquired naturally. 

Ciprofloxacin is a fluoroquinolone antibiotic that interferes with microbial DNA synthesis. It is indicated in the treatment of infections of the lower respiratory tract, skin and skin structure, bones and joints, urinary tract gonorrhea, chancroid, and infectious diarrhea caused by susceptible strains of specific organisms typhoid fever uncomplicated cervical and urethral gonorrhea women with acute uncomplicated cystitis acute sinusitis nosocomial pneumonia chronic bacterial prostatitis complicated intra-abdominal infections reduction of incidence or progression of inhalational anthrax following exposure to aerosolized Bacillus anthracis. Cipro IV Used for empirical therapy for febrile neutropenic patients. 

The other major health care products produced with the help of industrial fermentation are bacterial vaccines, therapeutic proteins, steroids, and gene therapy vectors. There are two categories of bacterial vaccines living and inactivated vaccines. Living vaccines consist of weakened, also known as attenuated, bacteria. Examples of living vaccines include those for diseases such as anthrax, which is caused by Bacillus anthracis, and typhoid fever, which is caused by Salmonella typhi. Inactivated vaccines are composed... 

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