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Tumors, invasion targeting

Fourth, the demonstration that many of these enzymes have prognostic value in cancer may qualify them as novel therapeutic targets. For example, similar to many other proteases, these enzymes may participate in the digestion of extracellular matrix, thus facilitating tumor invasion and metastasis. The identification of highly specific inhibitors may reveal new therapeutic opportunities. [Pg.64]

Tumor invasion, metastasis, and resistance to chemotherapeutic drugs and radiation are major obstacles for the successful treatment of cancer [65]. Some of these limitations can be overcome by therapeutic strategies that increase specificity and efficacy and at the same time reduce toxicity of the anticancer drugs. One of the approaches includes targeting the polymeric delivery systems specifically to the cancer cells. [Pg.268]

MA M10 M10.014 Membrane-type matrix m etallo pe pt id ase-1 Potential drug target for tumor cell invasion... [Pg.879]

See other pages where Tumors, invasion targeting is mentioned: [Pg.361]    [Pg.530]    [Pg.229]    [Pg.14]    [Pg.62]    [Pg.30]    [Pg.127]    [Pg.147]    [Pg.194]    [Pg.210]    [Pg.212]    [Pg.30]    [Pg.256]    [Pg.813]    [Pg.646]    [Pg.212]    [Pg.665]    [Pg.230]    [Pg.2281]    [Pg.63]    [Pg.66]    [Pg.66]    [Pg.75]    [Pg.356]    [Pg.1132]    [Pg.343]    [Pg.25]    [Pg.130]    [Pg.280]    [Pg.280]    [Pg.49]    [Pg.54]    [Pg.162]    [Pg.181]    [Pg.245]    [Pg.181]    [Pg.223]    [Pg.293]    [Pg.316]    [Pg.253]    [Pg.156]    [Pg.1194]    [Pg.96]    [Pg.263]    [Pg.264]   
See also in sourсe #XX -- [ Pg.201 ]



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Invasive

Tumor invasion

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