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Tumor necrosis factor a

Proadhesive Tumor necrosis factor a (TNFa) Tumor necrosis factor a (TNFa)... [Pg.629]

Abbreviations LDL, low density lipoprotein TNF-a, tumor necrosis factor-a IL-6, interleukin-6 APC, adenomatous polyposis coli tumor suppressor. [Pg.943]

Tumor Necrosis Factor a TNF Receptor Superfamily Cytokines Inflammation... [Pg.1203]

Fig. 14 Effect of the molecular weight of tamarind seed xyloglucan depolymerized by ( ) 7-irradiation, ( ) ultrasonication, and ( ) endo-glucanase treatment on the production of various cytokines (Tumor necrosis factor a, TNE-a Interleukin 8, IL-8 Interleukin 10, IL-10 and Interleukin 12, IL-12) in HaCaT cells (Immortalized keratinocytes line) [301]... Fig. 14 Effect of the molecular weight of tamarind seed xyloglucan depolymerized by ( ) 7-irradiation, ( ) ultrasonication, and ( ) endo-glucanase treatment on the production of various cytokines (Tumor necrosis factor a, TNE-a Interleukin 8, IL-8 Interleukin 10, IL-10 and Interleukin 12, IL-12) in HaCaT cells (Immortalized keratinocytes line) [301]...
RD, Young JB, Mann DL Tumor necrosis factor-a and tumor necrosis factor receptors in the failing human heart. Circulation 1996 93 704. 52... [Pg.108]

Inflammatory cytokines have been implicated in the pathophysiology of HF.9 Several proinflammatory (e.g., tumor necrosis factor-a [TNF-a], interleukin-1, interleukin-6, and interferon-y) and anti-inflammatory cytokines (e.g., interleukin-10) are overexpressed in the failing heart. The most is known about TNF-a, a pleiotrophic cytokine that acts as a negative inotrope, stimulates cardiac cell apoptosis, uncouples 3-adrenergic receptors from adenylyl cyclase, and is related to cardiac cachexia. The exact role of cytokines and inflammation in HF pathophysiology continues to be studied. [Pg.38]

Eosinophils may be increased in some patients, particularly during exacerbations. Activated inflammatory cells release a variety of mediators, most notably leukotriene B4, interleukin-8, and tumor necrosis factor-a (TNF-a). Various proteinases, such as elastase, cathepsin G, and proteinase-3, are secreted by activated neutrophils. These mediators and proteinases are capable of sustaining inflammation and damaging lung structures. [Pg.232]

Etanercept is a fully human dimeric fusion protein composed of human TNF-a p75 receptor fused to the Fc portion of human IgG 1.41 It acts as a tumor necrosis factor-a (TNF-a) inhibitor by binding to and inactivating TNF-a, thus preventing interactions with its cell surface receptors.41 This agent is useful for chronic moderate to severe plaque psoriasis and for psoriatic... [Pg.956]

See other pages where Tumor necrosis factor a is mentioned: [Pg.518]    [Pg.539]    [Pg.136]    [Pg.137]    [Pg.225]    [Pg.627]    [Pg.858]    [Pg.866]    [Pg.886]    [Pg.967]    [Pg.968]    [Pg.1202]    [Pg.1203]    [Pg.1239]    [Pg.268]    [Pg.285]    [Pg.22]    [Pg.68]    [Pg.529]    [Pg.40]    [Pg.316]    [Pg.373]    [Pg.61]    [Pg.243]    [Pg.294]    [Pg.869]    [Pg.891]    [Pg.926]    [Pg.956]    [Pg.1035]    [Pg.1047]    [Pg.1052]    [Pg.1060]    [Pg.1188]    [Pg.1196]    [Pg.1293]    [Pg.1337]   
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See also in sourсe #XX -- [ Pg.64 , Pg.228 ]



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Proinflammatory cytokine tumor necrosis factor-a (TNF

Tumor necrosis

Tumor necrosis factor

Tumor necrosis factor-a (TNF

Tumor necrosis factor-a inhibitor

Tumor necrosis factor-a-converting enzyme

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