Tumor immunology

W. R. Hanson, Prostaglandin Inhibitors in Tumor Immunology andimmunotherapj, CRC Press, Inc., Boca Raton, 1994, pp. 171—186. 

Department of Tumor Immunology Nijmegen Centre for Molecular Life Sciences... 

Keywords tumor immunology, escape mechanisms, MHC class 1, CTL, NK... 

Medical Biology Section Tumor Immunology Laboratory Hanzeplein 1 9713 GZ Groningen... 

Monoclonal antibody therapy is based on the ability to target markers and bind to cell membrane antigens with great specificity. Many times the enhanced specificity demonstrated toward the tumor antigens allows normal cells to be protected against harmful effects, unlike conventional chemotherapy. There are several mechanisms by which monoclonal antibodies destroy or prevent further replication of malignant cells. Some monoclonal antibodies utilize tumor immunology and components of the host natural defense mechanism to exert their desired effect. For example, monoclonal antibodies can utilize tumor effector cells to promote tumor cell lysis or have the ability to directly modulate tumor function. 

Tumor immunology is a scientific discipline that is driven by clinical translation. For many decades, scientists both at... 

Radboud University Department of Tumor Immunology Nijmegen Medical Centre Geert Grooteplein 26/28 GA 6525 Nijmegen The Netherlands... 

Smith, W. L. and Laneuville, O. (1994) Cyclooxygenase and lipoxygenase pathways of arach-idonic acid metabolism, in Prostaglandin Inhibitors in Tumor Immunology and Immunotherapy (ed.), CRC Press, Boca Raton, FL, pp. 1-39. 

MARCUS E. PETER (317), German Cancer Center for Tumor Immunology Program, D-69009 Heidelberg, Germany... 

The prefixes assigned to ATCC cell lines reflect the historical source of support for their addition to the Collection and, to a certain extent, the degree of characterization applied. Representative Certified Cell Lines (CCL) Cell Repository Lines (CRL) in the general and patent collections hybridomas in the collection supported by the National Institute for Allergy and Infectious Diseases (HB) and cells important for studies in tumor immunology (TIB) are listed in this table. The CRL total does not include some 1900 additional cell lines in special collections. See Hay et al. (1992) for names of originators, references, and more detail. 

Sogn JA. Tumor immunology the glass is half full. Immunity 1998 9 757-763. 

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