Tubulin genes

Tubulins arose very early during the course of evolution of unicellular eukaryotes and provide the machinery for the equipartitioning of chromosomes in mitosis, cell locomotion, and the maintenance of cell shape. The primordial genes that coded for tubulins likely were few in number. As metazoan evolution progressed, natural selection processes conserved multiple and mutant tubulin genes in response to the requirements for differentiated cell types (Sullivan, 1988). 

J. P. Davies A. R Grossman (1994) Sequences controlling transcription of the Chlamydomonas l -tubulin gene after deflagellation and during the cell cycle. Mol. Cell. Biol., 14 5165-5174... 

RAPD marker of Lees, 1995 in Doohan etal, 1998 P-tubulin gene... 

Tooley, P. W., Goley, E. D., Carras, M. M., Frederick, R. D., and Weber, E. L. (2001). Characterization of Claviceps species pathogenic on sorghum by sequence analysis of the /1-tubulin gene intron 3 region and EF-la gene intron 4. Mycologia 93, 541-551. 

Brehm, K., Kronthaler, K., Jura, H. and Frosch, M. (2000) Cloning and characterization of P-tubulin genes from Echinococcus multilocularis. Molecular and Biochemical Parasitology 1 07, 297-302. 

Caccio, S., Camma, C., Onuma, M. and Severini, C. (2000) The (3-tubulin gene of Babesia and Theileria parasites is an informative marker for species discrimination. International Journal for Parasitology 30, 11 81-11 85. 

Collins, C.M., Miller, K. and Cunningham, C.O. (2004) Characterisation of a (3-tubulin gene from the mono-genean parasite, Gyrodactylus salaris Malmberg, 1 957. Parasitology Research 92, 390-399. 

Robinson, M.W., Hoey, E.M., Fairweather, I., Dalton, J.P., McConigle, S. and Trudgett, A. (2001) Characterisation of a P-tubulin gene from the liver fluke, Fasciola hepatica. International Journal for Parasitology 31,1 264-1 268. 

Yamamoto, E. and Baird, W. V. (1999). Molecular characterization of four beta-tubulin genes from dinitroaniline susceptible and resistant biotypes of Eleusine indica. Plant Mol. Biol. 39, 45-61. 

Yemets, A., Radchuk, V., Bayer, O., Bayer, G., Pakhomov, A., Baird, W. V., and Blume, Y. B. (2008). Development of transformation vectors based upon a modified plant a-tubulin gene as the selectable marker. Cell Biol. Int. 32,566-570. 

MSG Kwa, JG Veenstra, M Van Dijk, MH Roos. (3-Tubulin genes from the parasitic nematode Haemonchus contortus modulate drug resistance in Caenorhabditis elegans. J Mol Biol 246 500-510, 1995. 

Alexandraki, D and Ruderman, J. V. (1983) Evolution of a-and (3-Tubulin Genes as Inferred by the Nucleotide Sequences of Sea Urchin cDNA clones, Journal of Molecular Evolution, 19,397-410. 

Monzo, M. Rosell, R. Sanchez, J. J. Lee, J. S. O Brate, A. Gonzalez-Larriba, J. L. Alberola, V. Lorenzo, J. C. Nunez, L. Ro, J. Y Martin, C. Paclitaxel resistance in non-small-cell lung cancer associated with beta-tubulin gene mutations. J. Clin. Oncol., 1999, 17 1786-1793. 

N-phenyl-carbamates diethofencarb B-tubulin 19,23 Mutation in 6-tubulin gene(E198L) ... 

Park, H. G., Stamenova, E. K., and Jong, S.-C. 2004. Phylogenetic relationships of Monascus species inferred from the ITS and the partial fl-tubulin gene. Bot. Bull. Acad. Sin. 45, 325-330. 

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