Tris methylmagnesium bromide

A 3 M diethyl ether solution of methylmagnesium bromide is added dropwise to a stirred solution of the tris-(trimethylsilyl) derivative of 15-oxo-PGF2a in diethyl ether at 25°C. 

Another unique compound was found7(g) among the products of the reaction between 3,5,6-tri-O-methyl-D-glucose and acetylmethylene-phosphorane. An inflection at 222 nm in the electronic spectrum, and strong infrared absorption at 5.8 /am, indicated an a,/3-unsaturated, cyclic ketone structure.89 When this compound was allowed to react with methylmagnesium bromide, the product showed7 8 an absence... 

Magnesium anthracenide (9.10-dihydro-9,10-anthracenediyl)tris(tetrahydrofuran)magnesium) Mesitylmagnesium bromide (2,4,6-trimethyl-phenylmagnesium bromide) 4-Methoxyphenylmagnesium bromide Methylmagnesium bromide... 

A remarkable exception from the tendency to form type 5 structures in normal Grignard reagents is the crystal structure of methylmagnesium bromide tris(tetrahydrofuranate) (15) (32). A possible explanation is the small size of the methyl group. In 15, the central magnesium has an... 

Trichloroacetophenone (5g) was prepared in 50% yield from 2,4,6-trichlorobenzoyl chloride and methylmagnesium bromide, and a hypobromite solution by dissolving bromine (50 g) in 10% sodium hydroxide solution (500 ml) at 0°. The ketone (5 g) was stirred with this hypobromite solution for 30 h at about 50° and then for 50 h at 70°, whereupon the tri-bromo ketone (8 g, 80%), m.p. 126-127°, separated. On prolonged boiling with 50% sodium hydroxide solution this product was hydrolysed almost quantitatively to 2,4,6-trichloro-benzoic acid. 

Preparative Methods (1) reaction of 2,3-dibromopropene with lithium (trimethylsilyl)cuprate in HMPA at 0°C (63-90%) (2) reaction of 2,3-dibromopropene with tri-chlorosilane in the presence of trichlorosilane and cop-per(l) chloride, followed by treatment with methylmagnesium bromide (63-71%).i 3- ... 

Dess-Martin periodane oxidation of l,3,5-tri-0-benzoyl-a-i>-ribofuranose affords the corresponding 2-keto derivative which reacts with MeTiCla (formed in situ from titanium tetrachloride and methylmagnesium bromide) to afford the C-2-branched derivative 1 together with the benzoate migration product 2. Perbenzoylation of a mixture of 1 and 2 produced an intermediate useful for making C-2 -methylribonucleosides by way of standard Vorbrugen coupling procedures with a number of nucleobases. ... 

Diethylgold bromide, 1666 Dimethylantimony chloride, 0896 Dimethylbismuth chloride, 0889 Ethylmagnesium iodide, 0855 Methylmagnesium iodide, 0445 Methylzinc iodide, 0446 ALKYLALUMINIUM HALIDES GRIGNARD REAGENTS TRI Al, KYI,ANTIMONY HALIDES... 

---