Benzoic 2,4,6-trichloro

These Soviet workers also prepared a series of l,2-dihydro-l,3,5-triazines by reaction of aryl aldehydes,252,254 Shiff bases,255-257 or ketimines258 with amidines of different acids (usually benzoic, trichloro-, or trifluoroacetic). They proposed that the dihydrotriazines form via intermediate azadienes, which undergo cyclization via [4 + 2] cycloaddition, accompanied by elimination of an akylidenimine [Eq. (75)]. 

Poly (ethylene glycol) (PEG) 4000 has been employed for the preparation of a PEG-anchored version of the previous dichlorotriazine reagents after its reaction with 2,4,6-trichloro[l,3,5]triazine in the presence of NMM [75]. This polymeric reagent (64) has been used for the preparation of anchored benzoic acid derivatives in the presence of NMM and THF as solvent, the supported activated esters being precipitated by addition of ether. Their further reaction with aliphatic and aromatic amines as bases afforded the corresponding amides in good yields, although sec-... 

Beilstein Handbook Reference) AI3-02583 Benzene, trichloromethyl)- Benzenyl trichloride Benzoic trichloride Benzotrichloride Benzolrlcloruro Benzyl trichloride Benzylidyne chloride BRN 0508152 CCRIS 1292 Chloruie de benzenyle Chlorure de benzylidyne EINECS 202-634-5 HSDB 2076 NSC 14663 Phenyl chloroform Phenyltrichloromethane RCRA waste a,a,a,-trichloro- Toluene trichloride ... 

Trichloroacetophenone (5g) was prepared in 50% yield from 2,4,6-trichlorobenzoyl chloride and methylmagnesium bromide, and a hypobromite solution by dissolving bromine (50 g) in 10% sodium hydroxide solution (500 ml) at 0°. The ketone (5 g) was stirred with this hypobromite solution for 30 h at about 50° and then for 50 h at 70°, whereupon the tri-bromo ketone (8 g, 80%), m.p. 126-127°, separated. On prolonged boiling with 50% sodium hydroxide solution this product was hydrolysed almost quantitatively to 2,4,6-trichloro-benzoic acid. 

There are three major classes of synthetic auxins the aryl acetic acids, which include indoleacetic acid (lAA) itself (Fig. 1 structure 2-1) and 1-naphthyl acetic acid (2-4), phenoxy acetic acids, represented by 2,4-dichlorophenoxy acetic acid (2,4-D) (2-7) and the benzoic acids, e.g. 2,3,6-trichloro benzoic acid (2-9). It remains the case however, that there is no stmcture-activity proposal which satisfactorily covers all molecules which are known to have auxin activity. As is well known, auxins have multiple effects, including promotion of cell elongation, cell division and gene expression. There may well be different receptors for each effect, and differences between receptors. An auxin binding protein (ABP), has now been characterised, and is possibly a receptor controlling cell elongation [3]. 

C-8 chlorine derivatives appear more difficult to synthetize [24, 26, 31], the main issue being the introduction of the chlorine atom. Access to 3-chloro-2,4,5-trifluorobenzoic acid was achieved by a pivotal fluorine exchange reaction from 2,3,4-trichloro-5-fluorobenzonitrile or by direct chlorination of 2,4,5-trifluoro-benzoic acid. 

Lactic acid, alkyl fatty acids (salicylic acid, glycolic add, benzoic add Chlorhexidine gluconate/acetate Fatty alkyl 1,3-diaminopropane A-Fatty alkyl 3-aminopropionate, A-hydroxyethyl-A-carboxymethyl fatty acid sodium salt of amidoethylamine Ethyl alcohol, propyl alcohol, benzyl alcohol, pine oil Sodium hypochlorite (liquid chlorine bleach), chlorine dioxide, hypochlorous acid, trichloro- and dichloroisocyanuric acids and their salts, sodium perborate and activator, peroxy acid (per acid), magnesium salt of peroxy phthalic acid, oxygen bleach generated from ozone... 

Stabilizers 1 -(2-(2,4-diohlorophenyl)-2-(2-propenyloxy)ethyl)-1 H-imidazole, 2,4,4 -trichloro-2 -hydroxydiphenyl ether, benzoic anhydride, nisin, silver, zinc ... 

Sucrose was actylated at 0-1 preferentially by subtilisin-catatysed transesterification from the trifluoro- or trichloro- ethyl esters of acetic, propionic, octanoic, benzoic, and acrylic acid in DMF. Subsequent hydrolysis of the yoosidic bond with a-glucosidase gave D-fructose l-esters. ... 

Starks found that tricaprylylmethylammonium chloride catalyzed the hydrolysis of A2-dodecanesulfonyl chloride by aqueous hydroxide. Quantitative yields of the sulfonic acid were obtained in the presence of the quaternary ammonium catalyst whereas little reaction was observed in its absence [6, 7]. The hydrolysis of trichloro-methylbenzene to benzoic acid (see Eq. 9.16) was likewise catalyzed by a quaternary ammonium salt [37]. 

Preparation by hydrogenolysis of 2,2, 4-tris-(benzyloxy)-3,5,5 -trichloro-4 -methoxy-6,6 -di-methylbenzo-phenone (SM) in the presence of 10% Pd/C in ethyl acetate containing concentrated hydrochloric acid (5 drops) (>90%) [1339], SM was obtained by Friedel-Crafts acylation of 5-(benzyloxy)-2-chloro-3-methoxytoluene with 2,4-bis-(benzyloxy)-3,5-dichloro-6-methyl-benzoic acid in the presence of trifluoroacetic anhydride in refluxing ethylene dichloride for 5 h (42%). 

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