Trimming methods, comparison

Statistical Analysis. Analysis of variance (ANOVA) of toxicity data was conducted using SAS/STAT software (version 8.2 SAS Institute, Cary, NC). All toxicity data were transformed (square root, log, or rank) before ANOVA. Comparisons among multiple treatment means were made by Fisher s LSD procedure, and differences between individual treatments and controls were determined by one-tailed Dunnett s or Wilcoxon tests. Statements of statistical significance refer to a probability of type 1 error of 5% or less (p s 0.05). Median lethal concentrations (LCjq) were determined by the Trimmed Spearman-Karber method using TOXSTAT software (version 3.5 Lincoln Software Associates, Bisbee, AZ). 

Bioassay responses were calculated as LD q s, ED q s or ET q s using the trimmed Spearman-Karber method (14). Duncan s multiple range test and analysis of variance were used for the repellency trials, and the paired comparison t-test was used to analyze the food preference experiments. 

Using a 500 MHz instrument and solvent (H2O) suppression, the spectra are collected using 0.5 ml urine with 50 pi 20 mol 1 sodium 2,2,3,3-(trim-ethylsilyl)tetradeuteropropionate in D2O. Peaks are assigned by comparison to standards and by use of various pulse sequences. Peaks can be seen for creatine, creatinine, and sarcosine. Creatine is generally elevated in the urine of infants. Sarcosine concentrations in the urine of normal healthy patients are too low to be seen by this method. 

A. Pietrzyk et al. reported an imprinted poly[bis(2,2 -bithienyl)methane] film for a piezoelectric microgravimetry of dopamine. The MIP film contained either a 3,4-dihydroxyphenyl or benzo-18-crown-6 substituent, for selective determination of dopamine and was electropolymerized on an imderlayer of poly(bithiophene) on a Pt/ quartz resonator. The detection limit of the method was reported to be 10 nM [401]. Kan et al, on the other hand, developed a composite of multiwalled carbon nanotube (MWCNTs) and MIP with dopamine templates using the copolymerization reaction of methacrylic acid and trimethylolpropane trimethacrylate (copoly(MAA-co-TRIM)) on the vinyl functionalized MWCNT surface and used the composite for the thermo-gravimetric analysis of the template. The composite was found to be selective towards dopamine in comparison with epinephrine and the response was linear in the range of 5.0 X 10 "-2.0 X 10 M [427]. 

Theirmann, H., Worek, R, Eyer, R, 2009. Comments on "efficacy of two new asymmetric bispyridinium oximes (K-27 and K-48) in rats exposed to diisopropylfluorophosphate comparison with pralidoxime, obidoxime, trim-edoxime, methoxime, and HI 6". Toxicol. Mech. Methods 19 (4), 334. 

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