Thyroid hormones Tricyclic antidepressants

Drugs that may be affected by estrogens include oral anticoagulants, tricyclic antidepressants, hydantoins, corticosteroids, and thyroid hormones. 

Levodopa or dopamine agonists produce diverse dyskinesias as a dose-related phenomenon in patients with Parkinson s disease dose reduction reverses them. Chorea may also develop in patients receiving phenytoin, carbamazepine, amphetamines, lithium, and oral contraceptives, and it resolves with discontinuance of the offending medication. Dystonia has resulted from administration of dopaminergic agents, lithium, serotonin reuptake inhibitors, carbamazepine, and metoclopramide and postural tremor from theophylline, caffeine, lithium, valproic acid, thyroid hormone, tricyclic antidepressants, and isoproterenol. 

Antidepressants selective serotonin reuptake inhibitors, tricyclic antidepressants Antihypertensives felodipine Antibiotics quinolones, isoniazid Bronchodilators albuterol, theophylline Corticosteroids prednisone Dopa agonists levodopa Herbals ma huang, ginseng, ephedra Nonsteroidal anti-inflammatory drugs ibuprofen Stimulants amphetamines, methylphenidate, caffeine, cocaine Sympathomimetics pseudoephedrine Thyroid hormones levothyroxine Toxicity anticholinergics, antihistamines, digoxin Withdrawal alcohol, sedatives... 

Monoamine oxidase inhibitors Phencyclidine Tricyclic antidepressants Increased metabolic rate Dinitrophenol and pentachlorophenol Salicylates Thyroid hormone... 

The antidepressant response to imipramine, amitriptyline and possibly other tricyclics can be accelerated by the use of thyroid hormones. However, isolated cases of paroxysmal atrial tachycardia, thyrotoxicosis and hypothyroidism have occurred on concurrent use. 

The speed and efficacy of imipreunine in the treatment of depression were enhanced by the addition of thyroid hormone. 26 This combination was effective in patients who became resistant to the tricyclic antidepressives.27 increasing... 

A preliminary clinical paper reported that high doses of L-tryptophan produced an antidepressive response similar to that elicited by imipramine.48 imipramine caused a decrease in the rate of disappearance of norepinephrine from the rat brain after a single intraperitoneal dose, but not after long-term administration by this route. This result may explain the delayed onset of action of the tricyclic antidepressives, and suggests that thyroid hormone or pharmacological agents that increase the turnover of norepinephrine in the brain, if... 

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