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Trichothecenes biosynthesis

C. Trichothecene biosynthesis cluster genes as sequence source for primer design... [Pg.103]

Various sequence sources other than genes from the trichothecene biosynthesis pathway were used to set up PCR-based systems for identification and detection of trichothecene producers. Highly specific... [Pg.106]

Kimura, M., Tokai, T., O Donnell, K., Ward, T. J., Fujimura, M., Hamamoto, H., Shibata, T., and Yamaguchi, 1. (2003). The trichothecene biosynthesis gene cluster of Fusarium grami-nearum F15 contains a limited number of essential pathway genes and expressed non-essential genes. FEBS Lett. 27,105-110. [Pg.132]

A common pathway of trichothecene biosynthesis From FPP to ITdiol 440... [Pg.411]

Clustering and nonclustering of trichothecene biosynthesis genes in Fusarium species 445... [Pg.411]

Classified into the chemical group sesquiterpenes, trichothecene skeleton is constructed from farnesyl pyrophosphate (FPP) with two rounds of cyclization237-239 Isotrichodiol (ITdiol)240 is a branching-point intermediate of Fusarium trichothecenes and non-Fusarium trichothecenes that precedes the second cyclization. In this section, we summarize outlines of trichothecene biosynthesis focusing on those of Fusarium species. [Pg.439]

Figure 29 A common pathway of trichothecene biosynthesis. FPP is cyclized to TDN (125) by a cyclase encoded by Tri5. In the biosynthesis of both Fusarium trichothecenes and non-Fusarium trichothecenes, three oxygenations catalyzed by a CYP encoded by Tri4 follow to yield ITdiol (128). Figure 29 A common pathway of trichothecene biosynthesis. FPP is cyclized to TDN (125) by a cyclase encoded by Tri5. In the biosynthesis of both Fusarium trichothecenes and non-Fusarium trichothecenes, three oxygenations catalyzed by a CYP encoded by Tri4 follow to yield ITdiol (128).
Desjardins AE, Hohn TM, McCormick SP Trichothecene biosynthesis in Fusarium species Chemistry, genetics and significance. Microbiol Rev 1993 57 595-604. [Pg.203]

This review lists the trichothecenes recorded in the literature up to Dec. 2000, together with their sources, coupled with a summary of the pathways involved in trichothecene biosynthesis, an area in which significant advances have been made during the past decade. The review contains both macrocyclic trichothecenes ( macrocycles ), previously recorded to Dec. 1991 (7), and non-macrocyclic trichothecenes, previously recorded to Dec. 1995 (2, 3). Some omissions from these earlier lists have been included, and some errors corrected. [Pg.64]

Desjardins AE, Plattner RD, Beremand MN (1987) Ancymidol Blocks Trichothecene Biosynthesis and Leads to Accumulation of Trichodiene in Fusarium sporotrichioides and Gibberella pulicaris. Appl Environ Microbiol 53 1860... [Pg.124]

Hohn TM, Desjardins AE, McCormick SP (1995) The Tri4 Gene of Fusarium sporotrichioides Encodes a Cytochrome P450 Monooxygenase Involved in Trichothecene Biosynthesis. Mol Gen Genet 248 95... [Pg.128]

Hesketh AR, Gledhill L, Bycroft BW, Dewick PM, Gilbert J (1993) Potential Inhibitors of Trichothecene Biosynthesis in Fusarium culmorum Epoxidation of a Trichodiene Derivative. Phytochemistry 32 93... [Pg.128]

Alexander NJ, Hohn TM, McCormick SP (1998) The TRIll Gene of Fusarium sporotrichioides Encodes a Cytochrome P-450 Monooxygenase Required for C-15 Hydroxylation in Trichothecene Biosynthesis. Appl Environ Microbiol 64 221... [Pg.128]

Beremand MN, Desjardins AE (1988) Trichothecene Biosynthesis in Gibberella pulicaris Inheritance of C-8 Hydroxylation. J Industrial Microbiol 3 167... [Pg.128]

Proctor RH, Hohn TM, McCormick SP, Desjardins AE (1995) Tri6 Encodes an Unusual Zinc Finger Protein Involved in Regulation of Trichothecene Biosynthesis in Fusarium sporotrichioides. Appl Environ Microbiol 61 1923... [Pg.129]

Matsumoto G, Wuchiyama J, Shingu Y, Kimura M, Yoneyama K, Yamaguchi I (1999) The Trichothecene Biosynthesis Regulatory Gene from the TVpe B Producer Fusarium Strains Sequence of Tri6 and Its Expression in Escherichia coli. Biosci... [Pg.129]

Figure 3.129 Trichothecene biosynthesis in other genera than Fusarium proposed pathway for type B trichothecene trichothecin 372, type C trichothecene crotocin 373, and type D macrolide trichothecenes roridin A 374 and verrucarin A 375. Figure 3.129 Trichothecene biosynthesis in other genera than Fusarium proposed pathway for type B trichothecene trichothecin 372, type C trichothecene crotocin 373, and type D macrolide trichothecenes roridin A 374 and verrucarin A 375.
CYP58 Epoxidation of o-methyl-sterigmato-cystin precursor and trichodiene C-2 hydroxylation, C12-C13 epoxidation, Cll and C3 hydroxylations Aflatoxin and trichothecene biosynthesis A. flavus, A. parasiticus , and F. gra-minearum, F. sporotrichoides [512, 836] [513, 514]... [Pg.332]

CYP65 Trichothecene Cl 5 hydroxylation and fumonisin CIO hydroxylation Trichothecene biosynthesis and fiimoni-sin biosynthesis F. graminearum, F. sporotrichoides and F. verticillioides [514, 840, 841]... [Pg.332]

CYP68 Trichothecene C8 hydroxylation and GA14 and GA12 hydroxylations Trichothecene biosynthesis and gibberel-lin biosynthesis F graminearum, F. sporotrichoides and F. fujikori [462, 514, 842, 843]... [Pg.332]

CYP526 Trichothecene C4 hydroxylation Trichothecene biosynthesis F. graminearwn, F. sporotrichoides 15141... [Pg.333]

Kimura M, Tokai T, Takahashi-Ando N, Ohsato S, Fujimura M (2007) Molecular and genetic studies of trichothecene biosynthesis pathways, genes, and evolution. Biosci Biotechnol Biochem 71 2105-2123... [Pg.395]

Takahashi-Ando N, Ochiai N, Tokai T, Ohsato S, Nishiuchi T, Yoshida M, Fujimura M, Kimura M (2008) A screening system for inhibitors of trichothecene biosynthesis hydroxylation of trichodiene as a target. Biotechnol Lett 30 1055-1059... [Pg.395]

Kim HS, Lee T, Dawlatana M, Yun SH, Lee YW (2003) Polymorphism of trichothecene biosynthesis genes in deoxynivalenol- and nivalenol-producing Fusarium gramineanun isolates. Mycological Research 107 190... [Pg.3151]

Desjardins AE (2009) Frran yellow rain to green wheat 25 years of trichothecene biosynthesis research. J Agiic Food Chem 57 4478-4484... [Pg.3153]

Tokai T, Koshino H, Takahashi-Ando N, Sato M, Fujimura M, Kimura M (2007) Fusarium Tri4 encodes a key multifunctional cytochrome P450 monooxygenase for four consecutive oxygenation steps in trichothecene biosynthesis. Biochem Biophys Res Commun 353 412-417... [Pg.3153]

Meek IB, Peplow AW, Ake C, Jr., Phillips TD, Berranand MN (2003) Tril encodes the cytochrome P450 monooxygenase fiff C-8 hydroxylation during trichothecene biosynthesis in Fusarium sporoirichioides and resides upstream of another new Tri gene. Appl Environ Microbiol 69 1607-1613... [Pg.3153]

See other pages where Trichothecenes biosynthesis is mentioned: [Pg.81]    [Pg.105]    [Pg.375]    [Pg.439]    [Pg.441]    [Pg.445]    [Pg.445]    [Pg.447]    [Pg.448]    [Pg.195]    [Pg.109]    [Pg.252]    [Pg.336]    [Pg.3123]    [Pg.3129]    [Pg.3129]    [Pg.3153]   
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See also in sourсe #XX -- [ Pg.6 , Pg.249 , Pg.250 , Pg.251 , Pg.252 , Pg.253 , Pg.254 , Pg.255 , Pg.256 , Pg.257 , Pg.258 ]

See also in sourсe #XX -- [ Pg.6 , Pg.249 , Pg.250 , Pg.251 , Pg.252 , Pg.253 , Pg.254 , Pg.255 , Pg.256 , Pg.257 , Pg.258 ]



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