Propanol 1,1,1-trichloro

Acetaldehyde reacts with phosphoms pentachloride to produce 1,1-dichloroethane [75-34-3] and with hypochlorite and hypoiodite to yield chloroform [67-66-3] and iodoform [75-47-8], respectively. Phosgene [75-44-5] is produced by the reaction of carbon tetrachloride with acetaldehyde in the presence of anhydrous aluminum chloride (75). Chloroform reacts with acetaldehyde in the presence of potassium hydroxide and sodium amide to form l,l,l-trichloro-2-propanol [7789-89-1] (76). 

The para and ortho positions of phenols condense at the carbonyl group of acetone to make bisphenols, eg, bisphenol A, 4,4 -(l-methylethyhdene)bisphenol [80-05-07]). If the H atom is activated, CICH— compounds add to the carbonyl group in the presence of strong base chloroform gives chloretone (l,l,l-trichloro-2-methyl-2-propanol [57-15-8]). 

In the presence of an alkali metal hydroxide at about 50°C, chloroform condenses with acetone to give l,l,l-trichloro-2-methyl-2-propanol, [57-15-8] ie, chlorobutanol, chloretone, or acetone—chloroform (9,10). Chlorobutanol is a white crystalline substance with a campborlike odor its sedative, anesthetic, and antiseptic properties have given the compound some importance in the pharmaceutical industry. 

Borane and sodium in 1-propanol are good reducing agents for all three types of amides. Another reagent that reduces disubstituted amides to amines is trichloro-... 

Sasson and Rempel [97] showed that the system [(PPh3)3RuCl2]/secondary alcohol is suitable for the selective transformation of 1,1,1,3-tetrachloro into 1,1,3-trichloro compounds. Similarly, Blum and coworkers [98, 99] employed [(PPh3)3RuCl2] as well as polystyrene-anchored Rh, Ru and Ir complexes for the hydrogen transfer from alcohols to trihalomethyl compounds, leading to dihalo-methyl derivatives. For example, one of the Cl atoms of 2,2,2-trichloro-l-phenyl-ethanol was displaced by H at 140-160 °C in 2-propanol. The polymer-anchored catalysts proved to be resistant to leaching [99]. 

Ethane 2-Fluoro-2-methoxy-l,l.1-trichloro- V/3. 201 (Cl > F) 2-Propanole 3-Fluoro-l,l.l-... 

Propanone reacts with trichloromethane in the presence of potassium hydroxide to give 1,1,1-trichloro-2-methyl-2-propanol. What is likely to be the mechanism of this reaction What further evidence could be gained to establish the mechanism (If you do not see a possible answer, refer to Section 14-7B for helpful information.)... 

For alcohols, EHOMO decreases as the number of chlorines increases. The dataset is l-chloro-2-propanol 2,2/2-trichloro-l/l-ethanediol 2,2,2-trichloro-ethanol 2,2-dichloroethanol 2-chloroethanol 3-chloro-l,2-propanediol 3-chloropropanol and 4-chloro-l-butanol. HOMO represents 94.4% of the variance in the linear regression equation therefore, the probability of getting a correlation of -0.9721 for a sample size of eight is less than 1% (see Figure 5.17). 

The electroreduction of l,l,l-trichloro-2-hydroxy-4-methyl-4-pentene (123) at a lead cathode led to two products, l,l-dichloro-4-methyl-2,4-pentadiene (124) and 1,1-dichloro-2-hydroxy-4-methyl-4-pentene (125) (equation 64). Compound 124 was favored (yields > 75%) in acidic medium using methanol or 2-propanol as solvent97. 

Conversely, the decrease in the rate constant for the hydroxide ion catalyzed reaction of l,l,l-trichloro-2-methyl-2-propanol in the presence of polyoxyethylene(23) dodecanol and polyoxyethylene sorbitan mono-decanoate has been rationalized by assuming that the nucleophilic reaction occurs only in the bulk solution and that a substantial fraction of the substrate is solubilized by the surfactant. The latter assumption was verified by measurements of the solubility of l,l,l-trichloro-2-methyl-2-propanol, and hence the distribution coefficients, in the micellar systems (Anderson and Slade, 1966). 

P,P,P-TRICHLORO-tert-BUTYL ALCOHOL 1,1,1-TRICHLORO-2-METHYL-2-PROPANOL... 

N-(TRICHLOROMETHYLMERCAPTO)-A -TETRAHYDROPHTHALIMIDE see CBGOOO TRICHLOROMETHYLNITRILE seeTII750 l,l,l-TRICHLORO-2-METHYI 2-PROPANOL see ABDOOO... 

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