Transcriptome/transcriptomics

Transcriptomics Simultaneous measurement of the expression of all genes (or a substantial part thereof) in the genome of an organism. 

Santos, E.M., Pauli, G.C., and Van Look, K.J.W. (2007). Gonadal transcriptome responses and physiological consequences of exposure to oestrogen in breeding zebrafish (Danio rerio). Aquatic Toxicology 83, 134—142. 

Transcriptome The entire collection of expressed mRNAs in an organism. 

Schuller U, Kho AT, Zhao Q, Ma Q, Rowitch DH (2006) Cerebellar transcriptome reveals cell-type and stage-specific expression during postnatal development and tumorigenesis. Mol CeU... 

Adjunctive to flux control analysis, other components of metabolism that contribute to product accumulation are needed including (1) substrate/precursor pool sizes (metabolomics), (2) co-factor capacities (metabolomics), (3) gene expression profiles (transcriptomics and quanfifafive real-time PCR), (4) protein profiles (pro-... 

Alba, R. et al., Transcriptome and selected metabolite analyses reveal multiple points of ethylene control during tomato fruit development, Plant Cell 17, 2954, 2005. 

Cellular activities are mediated by complex networks of interactions in response to physiological signals, and the nature of the response is dependent on the cell type and states. These aspects cannot be accounted for by investigating at the genomic or transcriptomic levels alone, as genomes and transcriptomes are fairly conserved between cell states and types within a system. 

Sims, A.H., Gent, M.E., Lanthaler, K. et al. (2005) Transcriptome analysis of recombinant protein secretion by Aspergillus nidulans and the unfolded-protein response in vivo. Applied and Environmental Microbiology, 71 (5), 2737-2747. 

Armando Aranda For example, mass spectrometry and things which I am not really familiar with, but that kind of thing. For example at Los Alamos National Laboratory they have a group, because they are concerned - you have the genome, you have the transcriptome, you have the proteome and then you have the metabolome. 

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