Transcriptional arrest

Nielsen P. E., Egholm M., Buchardt O. Sequence-specific transcription arrest by peptide nucleic acid bound to the DNA template strand. Gene 1994 149 139-145. 

Svejstrup, ).Q. (2007) Contending with transcriptional arrest during RNAPII transcript elongation. Trends Biochem. Sci., 32,165-171. 

Kalogeraki, V.S., Tomaletti, S., and Hanawalt, P.C. (2003) Transcription arrest at a lesion in the transcribed DNA strand in vitro is not affected by a nearby lesion in the opposite strand. 

Wang, Z. and Rana, T.M. (1997) DNA damage-dependent transcriptional arrest and termination of RNA polymerase II elongation complexes in DNA template containing HIV-1 promoter. Proc. Natl. Acad. Sci. USA,... 

Leist M, Gantner F, Bohlinger I, German PG, Tiegs G, Wendel A (1994) Murine hepatocyte apoptosis induced in vitro and in vivo by TNF-alpha requires transcriptional arrest. J Immunol 153 1778-1787... 

Komissarova, N., and Kashlev, M. (1997b). Transcription arrest Escherichia coli RNA polymerase translocates backward, leaving the 3 end of the RNA intact and extruded. Proc. Natl. Acad. Sci. USA 94, 1755—1760. 

Samkurashvili, I., and Luse, D. S. (1996). Translocation and transcriptional arrest during transcript elongation by RNA polymerase II. J. Biol. Chem. 271(38), 23495-23505. 

Apoptotic executioner caspases (caspase-3, -6, -7) constitute a subgroup of the caspase family. These proteases are the workhorses of the apoptotic process as they are responsible for cleaving many down-stream substrates important for cellular morphology, organelle homeostasis, cell cycle arrest, and regulation of transcription and translation. 

Edgar No. There is one example in a subset of cells in the middle of the wing — the wing margin cells. In this region the wingless activity shuts down Myc transcription. This is a potential mechanism. But this is a subset of cells and it is a transient arrest. 

FIG. 3. Stopping the cell division cycles. In Drosophila embryos, the timely arrest of cell proliferation in the epidermis requires the transcriptional activation of dacapo (Lane et al 1996, de Nooij et al 1996) and fi y-related (Sigrist Lehner 1997) which occurs during the final division cycle in parallel to down-regulation of cyclin E expression. 

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