Tobacco regulation

Benowitz NL, Henningfield JE (1994) Establishing a nicotine threshold for addiction. The implication of tobacco regulation. New Engl J Med 331 123-125... 

Henningfield JE, Zeller M (2006) Nicotine psychopharmacology research contributions to United States and global tobacco regulation A look back and a look forward. Psychopharmacology 184 286-291... 

Requires pre-market evaluation of all new chemical products other than food additives, drugs, pesticides, alcohol, and tobacco regulates existing hazards not covered by other federal laws dealing with toxic substances... 

A Special agency now called the Bureau of Alcohol, Tobacco, and Firearms (BATF) within the U.S. Treasury Department was empowered to regulate the alcohoHc beverage industries. Although less adversarial, but strictly enforced even today (ca 1997), the regulations and their appHcation remain voluminous and detailed. They specify not only label compliance and matters relating to taxation that are of direct interest to consumers, but contain all the details of permitted processes for and additions to wines. 

Cla.ssifica.tlon, In commerce, several classifications of flavoring and compounded flavorings are Hsted according to composition to allow the user to conform to state and federal food regulations and labeling requirements, as well as to show their proper appHcation. Both suppHer and purchaser are subject to the control of the FDA, USD A, and the Bureau of Alcohol, Tobacco, and Firearms (BATF). The latter regulates the alcohoHc content of flavors and the tax drawbacks on alcohol, ie, return of a portion of the tax paid on ethyl alcohol used in flavoring. 

Both sorbic acid and potassium sorbate may be used under U.S. Department of Treasury, Bureau of Alcohol, Tobacco, and Firearms regulations as sterilizing and preservative agents for treatment of wine and juice at up to 300 ppm/L (158). 

In the United States, the Alcohol Tax Unit came into being with the repeal of Prohibition in 1933, and it became the Alcohol and Tobacco Tax division of the Internal Revenue Service in 1952. The Bureau of Alcohol, Tobacco, and Firearms (ATF), established in 1972, and the Department of the Treasury closely regulate the manufacture of distilled spirits. 

Distilled spirits are governed by the Bureau of Alcohol, Tobacco, and Firearms regulations. Every botde of distilled spirits must contain a specified percent of alcohol or proof as stated on the label. Proof is the ethyl alcohol content of a Hquid at 15.6°C, stated as twice the percent of ethyl alcohol by volume. 

Packaging for distilled spirits intended for domestic distribution is regulated by the Federal Bureau of Alcohol, Tobacco, and Firearms (ATF). This strict supervision estabhshes acceptable container size, labeling, and sealing requirements, as well as the disclosure of information on the shipping container. Furthermore, local and state distilled spirits labeling and packaging requirements must also be met. 

The Bureau of Alcohol, Tobacco, and Firearms PubHcation, Title 27, Code of Federal Regulations, Subpart C, Washington, D.C., 1991. 

Environmental tobacco smoke mid gasoline vapors both contain mixtures of trace luiiounts of many of the individual compounds regulated as Air Toxics under Title 111, section 112 of the 1990 Clean Air Act Amendnmts. Much of the general public is more likely to be exposed to these mixtures during the course of their lives tlian to specific compounds on the air toxics list. Hence, estimation of the cancer risk resulting from exposure to these mixtures is a useful and relevant exercise. 

Ellis, J.G., Llewellyn, D.J., Dennis, E.S. Peacock, W.J. (1987). Maize Adh-1 promoter sequences control anaerobic regulation addition of upstream promoter elements from constitutive genes is necessary for expression in tobacco. EM BO Journal, 6, 11-16. 

Formaldehyde is a harmful compound released from walls and furnitures in new houses because adhesives containing HCHO are often used in constmction materials. In addition, H CHO is emitted by tobacco smoke and combustion exhaust gases. Long exposure to HCHO causes serious health problems called sick house diseases. In Japan, the concentration of HCHO in indoor air is regulated [54] to under 0.08 ppm based on the recommendation of the World Health Organization (WHO). 

Eberhard, S., Doubrava, N., Marfk, V., Mohnen, D., Southwick, A., DarviU, A., and Albersheim, P. (1989) Pectic cell wall fragments regulate tobacco thin-ceU-layer explant morphogenesis. Plant Cell, 1 747-755. 

Flumetralin is a plant growth regulator, used to control sucker growth in tobacco... 

Industrial ethyl alcohol Industrial ethyl alcohol that is reclaimed is exempt from RCRA Subtitle C because the U.S. Bureau of Alcohol, Tobacco, and Firearms (BATF) already regulates it from the point of generation to redistillation. 

Palozza, P, A. Sheriff, S. Serini et al. 2005. Lycopene induces apoptosis in immortalized fibroblasts exposed to tobacco smoke condensate through arresting cell cycle and down-regulating cyclin Dl, pAKT and pBad. Apoptosis 10(6) 1445-1456. 

---