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Tissue regeneration structural component

Besides SAPs, Hartgerink et. al. have developed peptide amphiphiles (PAs) [68], a new class of self-assembling peptide-based biomaterials with potential for bone tissue regeneration. A PA is comprised of three peptide regions, each with different functions, and a hydrophobic aliphatic tail. These components interact with each other, self-assembling to form a cylinder (Figure 7). Particularly, the structure of a PA contains four cysteine amino acids that are adjacent to a hydrophilic aliphatic core. This allows for disulfide bonding, which stabilizes the PA structure when it self-assembles. Furthermore, phosphoserine, which is copious in... [Pg.110]

The elimination of the lobular structure is the essential component of all forms of cirrhosis. Pronounced necrosis or extensive proliferation of connective tissue do not serve as adequate criteria for liver cirrhosis. Nor are inflammatory processes an absolute prerequisite for the development of this condition. The aetiology nor the presence of regeneration nodes are criteria for liver cirrhosis. (see chapter 35)... [Pg.407]


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Regenerator components

Structural components

Tissue structure

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