Tissue engineering Cell delivery

Chitosan 20-100 0 Cell targeting. Tissue engineering. Drug delivery, hyperthermia Coroto et al, 2011 Arami et al, 2011 Del campo et al, 2001 ... 

Drug delivery systems, sewing material, tissue engineering Drug delivery systems, cell microencapsulation... 

Bone tissue engineering Gene delivery Increased DNA penetration into the cells and luciferase activity with DNA-PEG-gelatin nanoparticle Hosseinkhani and Tabata (2006)... 

Bone tissue engineering Gene delivery Polymerized nanogel with stability in aqueous media, low toxicity, and enhanced DNA uptake in HeLa cell McAllister et al. (2002)... 

Abstract Synthetic polymers and biopolymers are extensively used within the field of tissue engineering. Some common examples of these materials include polylactic acid, polyglycolic acid, collagen, elastin, and various forms of polysaccharides. In terms of application, these materials are primarily used in the construction of scaffolds that aid in the local delivery of cells and growth factors, and in many cases fulfill a mechanical role in supporting physiologic loads that would otherwise be supported by a healthy tissue. In this review we will examine the development of scaffolds derived from biopolymers and their use with various cell types in the context of tissue engineering the nucleus pulposus of the intervertebral disc. 

Silva et al. (2006) studied starch-based microparticles as a novel strategy for tissue engineering applications. They developed starch-based microparticles, and evaluated them for bioactivity, cytotoxicity, ability to serve as substrates for cell adhesion, as well as their potential to be used as delivery systems either for anti-inflammatory agents or growth factors. Two starch-based materials were used for the development of starch-based particulate systems (1) a blend of starch and polylactic acid (SPLA) (50 50 w/w) and (2) a chemically modifled potato starch, Paselli II (Pa). Both materials enabled the synthesis of particulate systems, both polymer and composite (with BG 45S5). A simple solvent extraction method was employed for the synthesis of SPLA and SPLA/BG microparticles, while for Pa and Pa/BG... 

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