Thromboembolism diagnosis

Venous thromboembolism diagnosis and management of deep venous thrombosis. MedJAust. 2005 182 476-481. 

GPIIb/IIIa Integrin Receptor Antagonists In the Rapid Diagnosis of Thromboembolic Events... 

The role of the platelet integrin GPIIb/IIIa receptor and its potential utility as a radio-diagnostic agent in the rapid detection of thromboembolic events has been demonstrated [6]. This approach may be useful for the noninvasive diagnosis of various thromboembolic disorders. 

Given that VTE is often clinically silent and potentially fatal, prevention strategies have the greatest potential to improve patient outcomes.2 To rely on the early diagnosis and treatment of VTE is unacceptable because many patients will die before treatment can be initiated. Furthermore, even clinically silent disease is associated with long-term morbidity from the postthrombotic syndrome and predisposes the patient to future thromboembolic events. Despite an immense body of literature that overwhelmingly supports the widespread use of... 

National trends of cardiovascular mortality are incompatible with these risk estimates excess deaths may not be attributable entirely to smoking the clinical diagnosis of thromboembolism is often unreliable. 

Estrogens should be avoided in individuals with current thrombophlebitis or thromboembolism, estrogen-depen-dent tumors, abnormal genital bleeding without a diagnosis, and pregnancy. They are also contraindicated in apparently healthy women if they have an earlier history of jaundice in pregnancy, hepatic disease, thromboembolism, or porphyria. 

Press RD, Bauer KA, Kujovich JL, Heit JA. Clinical utility of factor V Leiden (R506Q) testing for the diagnosis and management of thromboembolic disorders. Arch Pathol Lab Med 2002 126 1304-18. 

WHO group IV includes patients with chronic thrombotic and embolic disease. For those with chronic thromboembolic disease, diagnosis and well-timed surgery may be curative if performed at a center proficient in performing pulmonary thromboendarterectomies. However, even with successful thromboendarterectomy... 

The outcome of homocystinuria has improved with current therapeutic regimes and with early diagnosis via newborn screening [48]. The prognosis is directly associated with the occurrence of vascular ischemia since, as noted, the majority of morbidity and mortality are associated with thromboembolic events. Outcome is also... 

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