Thiocarbamic acids

Reaction wifli Salts and Esters of Thiocarbamic Acid 2-Hydroxythiazoles and Derivatives... 

Hydroxythiazoles give 2-chIorothiazole derivatives almost quantitatively upon treatment with phosphorus oxychloride (221, 229, 428). This constitutes a convenient synthesis method for these compounds when the conversion of 2-aminothiazoles to 2-chlorothiazole derivatives fails. Esters of thiocarbamic acid or thiourethanes also react with a-halocarbonyl compounds to give the corresponding 2-alkoxythiazoles (50, 68, 209, 272). 

Thio-ameisensiiure, /. thioformic acid, -anti-monsaure, /. thioantimonic acid, -arsenig-saure, /. thioarsenious acid, -arsenaaure, /. thioarsenic acid, -ather, m. thio ether, -car-baminsaure,/. thiocarbamic acid. 

Analysis of pesticides in water was performed by fully automated online solid-phase extraction-liquid chromatography-tandem mass spectrometry (SPE-LC-MS/ MS) [25, 31]. These pesticides (a total of 22 belonging to the classes of triazines, OP, chloroacetanilides, phenylureas, thiocarbamates, acid herbicides, and anilides) were selected on the basis of previously published studies [20, 25], information gathered from the water authorities, and known use in rice crops. 

Research Focus Preparation of IV-substituted imide dialkyl-thiocarbamic acid esters as high-activity polymerization initiators. 

TABLE 2. Pendulum Hardness and Cross-Hatch Testing Results for Polymers Prepared Using Selected Dialkyl-Thiocarbamic Acid Esters... 

Janssen144-146 has successfully used a method resembling the co-technique (self-consistence within the HMO framework) to study the spectral properties of derivatives of thiocarbamic acid and thiourea these compounds lie outside the scope of this review, however. The possibility of using the HMO method to correlate excitation energies of the first (usually intense) bands of various classes of heterocyclic compounds has been investigated see, e.g., refs. 15,17, and 160. The... 

Carbamate pesticides are used as (1) insecticides, (2) fungicides and (3) herbicides. Insecticides are generally derived from carbamic acid fungicides, from thiocarbamic acid. The herbicide carbamates are a more complex class of compounds. Tables 21 and 22 list some commercial carbamate pesticides in approximate order of decreasing toxicity. It should be noted that the relative classification of highly and moderately toxic is no measure of the relative carcino-, muta- or teratogenicities of these carbamates, since it is based solely on acute LD q data (Morgan, ref. 20). 

It has been reported <1998CC2315> that a similar [2+2] intramolecular cyclization of (2-cyclohex-l-enyl-2-methyl-propionyl)phenyl-thiocarbamic acid O-methyl ester leads to the formation of tricyclic thietane in 85% yield (Table 2). 

Azine approach. Vicinal amino halides in which the halogen is in an activated azine position, e.g. (449), can form a thiocarbamic acid (77JHC1045), or an equivalent derivative, e.g. (450) (77JHC129). This intermediate subsequently undergoes cyclization by nucleophilic displacement of the halogen substituent. 

The complex, tetrakis[thiourea]tellurium dichloride, reacted with bis[2-hydroxyethyl]di-thiocarbamic acid in aqueous methanol to precipitate tellurium bis[his(2-hydroxyethyl)di-thiocarbamate] as an orange solid11. 

Isocyanato- and 2-isothiocyanatobenzonitriles 1 react with hydrogen halides in dibutyl ether to give 4-haloquinazolin-2(li/)-ones and -quinazoline-2(l//)-thiones 2, respectively. The ring closure is based on a nucleophilic attack of the intermediary nitrile-halide adducts at the carbamic or thiocarbamic acid chloride function. 

TABtE 11-24 2-HYDROXYTHIAZOLE DERIVATIVES FROM o-HALO-CARBONYL COMPOUNDS AND SALTS AND ESTERS OF THIOCARBAMIC ACID (158a)... 

The reactivity of a,/9-unsaturated ketones and carboxylic acids shows much similarity to that of a-halo ketones and acids. The reactive position here though is displaced to the j3-carbon atom so that reaction with thiocarbamic acids gives rise to the formation of six-membered rings ... 

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