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The Production of Depression and Suicide

As already noted, there are reports in the clinical literature indicating that the BZs can cause depression. Some reviews mention the phenomenon but express skepticism, while nonetheless declaring that it should be taken seriously. Arana and Hyman (1991), for example, stated  [Pg.326]

Depression All benzodiazepines have been associated with the emergence or worsening of depression whether they were causative or only failed to prevent the depression is unknown. When depression occurs during the course of benzodiazepine treatment, it is prudent to discontinue the benzodiazepine. [Pg.326]

Ashton (1995) observed that BZs can blunt the emotions in general, producing emotional anesthesia. He reported, Former long-term benzodiazepine users often bitterly regret their lack of emotional response to family events during the period that they were taking the drugs. Ashton also observed that BZs can precipitate suicide in already depressed patients. [Pg.326]

The APA (1990a) task force report on BZs, in a discussion of toxicity, also observed that [Pg.326]

Great Britain s Committee on Safety of Medicines (CSM 1988) recommended that benzodiazepines should not be used alone to treat depression or anxiety associated with depression. Suicide may be precipitated in such patients.  [Pg.326]


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