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The Measurement of Partition Coefficients and Related Lipophilicity Parameters

The Measurement of Partition Coefficients and Related Lipophilicity Parameters [Pg.32]

The measurement of partition coefficients [40, 41, 49, 156, 173, 174, 217, 218] is not as easy as one would expect from their simple definition (eq. 19, chapter 3.1)  [Pg.32]

Practical problems arise for polar and highly lipophilic (log P 4) compounds. [Pg.32]

Even small impurities may drastically distort the experimental values, especially if the analytical method is more sensitive to impurities. [Pg.32]

Radioactive material is only suited if it has a high degree of radiochemical purity. [Pg.32]



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And lipophilicity

Coefficient measurement

Coefficient of the

Lipophilicity coefficient

Lipophilicity measurement

Lipophilicity partition coefficient

Measurement Parameters

Measurement of parameters

Measurement, of partition coefficient

Parameter coefficients

Parameter lipophilic

Parameter measured

Partition coefficients measurement

Partition measurements

Related Parameters

The parameters

The partition coefficient

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