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The Influence of Age

The elderly are also prone to toxicity from numerous drugs, including cardiac glycosides. A dose of digitoxin, which may be totally therapeutic and innocuous at the age of 60, may produce severe toxicity and even death at the age of 70. The abilities of the liver to metabolize drugs and of the kidney to excrete drug metabolites decline with aging. [Pg.20]

The influence of ageing time at 533 K on the form of phases was shown in Fig.3. 100 /o of the irregular and globular types was observed after 3 hours of ageing, which was stated in the quantitative image analysis examinations. [Pg.407]

Benke GM, Murphy SD. 1974. The influence of age and sex on the toxicity and multiple pathways of metabolism of methyl parathion and parathion in rats. Toxicol Appl Pharmacol 29 125. [Pg.195]

Craft S, Murphy C and Wernstrom J (1994). Glucose effects on complex memory and nonmemory tasks The influence of age, sex and glucoregulatory response. Psychobiology, 2, 95-105. [Pg.216]

Ziegler, J.R. 1976. Evolution of the migration response Emigration by Tribolium and the influence of age. Evolution 30, 579-592. [Pg.294]

Walker RF, Fishman B. 1991. The influence of age on neurotoxicity. In Cooper RL, Goldman JM, Harbin TJ, eds. The Johns Hopkins series in environmental toxicology Aging and environmental toxicology Biological and behavioral perspectives. Baltimore, MD Johns Hopkins University Press, 211-231. [Pg.291]

D. A. Svinarov, C. E. Pippenger, Relationships between Carbamazepine-Diol, Carba-mazepine-Epoxide, and Carbamazepine Total and Free Steady-State Concentrations in Epileptic Patients The Influence of Age, Sex, and Comedication , Ther. Drug Monit. 1996,18, 660 - 665. [Pg.678]

Allmyr M, Harden F, Toms LML, Mueller JF, McLachlan MS, Adolfsson-Erici M, Sandborgh-Englund G (2008) The influence of age and gender on triclosan concentrations in Australian human blood serum. Sci Total Environ 393 162-167... [Pg.298]

Ferriolli, E., R. O. Dantas, R. B. Oliveira, and F. J. Braga. The influence of ageing on oesophageal motility after ingestion of liquids with different viscosities. Eur J Gastroenterol Hepatol 1996 8(8) 793-798. [Pg.456]

Feely J, Crooks J, Stevenson IH. The influence of age, smoking and hyperthydroidism on plasma propranolol steady state concentration. BrJ Clin Pharmacol 1981 12 73-78. [Pg.44]

Various studies have been undertaken to identify clinical or paraclinical covariates associated with 5-FU PK variability, and the influences of age, sex, circadian rhythms, doses, and routes of administration on 5-FU PK have been well characterized (78,9,10,11,12). [Pg.250]

Andres E, Zimmer J, Noel E, Kaltenbach G, Koumarianou A, Maloisel F. Idiopathic thrombocytopenic purpura a retrospective analysis in 139 patients of the influence of age on the response to corticosteroids, splenectomy and danazol. Drugs Aging 2003 20(ll) 841-6. [Pg.166]

Notwithstanding the popular customs and beliefs which, under the influence of age-old traditions of pre-Buddhist origin, have grown around the profound revelations of the Bardo Thodol, it has value only for those who practise and realize its teaching during their life-time. [Pg.11]

Hebert CD, Bimbaum LS. 1987. The influence of aging on intestinal absorption of TCDD in rats. Toxicol Lett 37 47-55. [Pg.630]

Table 19.1 Crude analyses of the influences of age and health status on opinions concerning a liberalized supply of emergency contraception... Table 19.1 Crude analyses of the influences of age and health status on opinions concerning a liberalized supply of emergency contraception...
Sullivan JT, et al. The influence of age and gender on the pharmacokinetics of moxifloxacin. Clin. Pharmacokinet.,... [Pg.367]

Some studies find a higher total number of ampoules of FSH administered before oocyte retrieval in patients with elevated FSH levels (SI9), but others do not (Cl, El, H16, S10). When the influence of age and FSH is compared, FSH is a better predictor for response in assisted reproduction than age (Cl, G8, T5), although this is not the case for predicting pregnancy in all studies (HI, S19). [Pg.299]

Ortega-Heras, M., Gonzalez-Sanjose, M. L., Gonzalez-Huerta, C. (2007). Consideration of the influence of aging process, type of wine and oenological classic parameters on the levels of wood volatile compounds present in red wines. Food Chem., 103, 1434-1448. [Pg.310]

Pelayo JC, Andrews PM, Coffey AK, et al. 1983. The influence of age on acute renal toxicity of uranyl nitrate in the dog. Pediatric Research 17(12) 985-992. [Pg.382]

Schnider TW, Minto CF, Shafer SL, Gambus PL, Andresen C, Goodale DB, Youngs EJ. The influence of age on propofol pharmacodynamics. Anesthesiology 1999 90 1502-16. [Pg.385]

Miya T, Sasaki Y, Karato A, Saijo N. Pharmacokinetic study of mitomycin C with emphasis on the influence of aging. Jpn J Cancer Res 1992 83 1382-5. [Pg.388]

Shannon M, Lovejoy FH. The influence of age vs peak serum concentration on life-threatening events after chronic theophylline intoxication. Arch Intern Med 1990 150 2045-8. [Pg.388]

The influence of age on metabolic clearance is less clear than its influence on renal function. Metabolic clearance is more variable between individuals because of the genetic control and the influence of environmental factors on the metabolic capacity. The term metabolism also encompasses many different enzyme reactions that might be influenced to different extents by age, liver disease, or genetic variables. Unlike renal disease, in which creatinine clearance provides a reasonable estimate of kidney function, not one good indicator exists for the degree of liver function impairment with respect to drug metabolizing capacity. [Pg.586]

See other pages where The Influence of Age is mentioned: [Pg.406]    [Pg.350]    [Pg.313]    [Pg.142]    [Pg.268]    [Pg.268]    [Pg.147]    [Pg.16]    [Pg.56]    [Pg.20]    [Pg.351]    [Pg.20]    [Pg.216]    [Pg.51]    [Pg.244]    [Pg.420]    [Pg.420]    [Pg.62]    [Pg.82]    [Pg.70]    [Pg.239]    [Pg.746]    [Pg.396]    [Pg.3106]   


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