The Historical Uses of Belladonna Alkaloids

Belladonna was one of the most valuable agents in the materia medica, ranking high in its efficacy and its wide range of usefulness. It was employed to relieve pain, relax spasm, stimulate the circulation, decrease secretion, and check local inflammation. Atropine was used for the same purposes, as well as to antagonize the effects of certain poisons, to dilate the pupils, and to paralyze 

THE MODERN USES OF SYNTHETIC MUSCARINIC RECEPTOR ANTAGONISTS 

The various applications of synthetic muscarinic receptor antagonists are listed in the following text. Ophthalmology 

Atropine To prevent excess salivation and bradycardia Scopolamine hi obstetrics, to produce sedation and amnesia Cardiology Atropine  

Trihexyphenidyl, benztropine In parkinsonism and drug-induced pseudoparkinsonism Scopolamine In vestibular disorders such as motion sickness 

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