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Belladonnae

Atropiae (41), isolated from the deadly nightshade Airopa belladonna L.) is the racemic form, as isolated, of (—)-hyoscyamine [which is not isolated, of course, from the same plant but is typically found ia solanaceous plants such as henbane (HyosQiamus mgerl. )]. Atropiae is used to dilate the pupil of the eye ia ocular inflammations and is available both as a parasympatholytic agent for relaxation of the intestinal tract and to suppress secretions of the saUvary, gastric, and respiratory tracts. In conjunction with other agents it is used as part of an antidote mixture for organophosphorus poisons (see Chemicals in war). [Pg.537]

Atropa acuminata Royle ex Lindl. (A. lutescens Jacquemont.) Indian belladonna. Whole plant, grown from Indian seed in the United States, 0-32 to 0-38 large stems, 0-14, According to Corfield, Kassner and Collins,the leaves and roots, as imported from India, contain on the average 0-45 and 0-47 of non-volatile alkaloid, respectively. Much volatile alkaloid (MarkwelUi). Recognised in the British Pharmacopoeia 1932, Addendum V. [Pg.65]

Atropa Belladonna Linn. Leaves, 0-4 roots, 0-5 seeds, 0-8 whole plant, 0-2 to 1-0 h5mscyamine with some hyoscine atropine has been found but may have resulted from racemisation during extraction apoatropine and possibly belladonnine (Kreitmair Atropa bcetica. Leaves, 0-82-1-06 roots, 0-94 fruit, 1-09 hyoscyamine and atropine. [Pg.65]

The British Pharmacopoeia (1932) recognises three of these solanaceous drugs and specifies for them minimum requirements per cent, of total alkaloids, calculated as hyoscyamine, viz. belladonna, leaves 0-3, root 0-4 henbane, leaves and flowering tops 0-05 stramonium, leaves and flowering tops 0-25. The United States Pharmacopoeia, XIII, specifies the same minimum limits for belladonna leaves and stramonium and for henbane, 0-04. [Pg.67]

Neither tropine nor 4-tropine is mydriatic, though the former is stated to produce mydriasis in cats when injected in large doses. The pharmacological properties of these two bases have been compared by Hazard, who points out that these cis-trans isomerides show qualitative differences in pharmacological action, whereas among optical isomerides there are usually only quantitative differences in activity. It has been stated that rabbits are immune from poisoning by belladonna and, in that connection,... [Pg.106]

The hyoscyamine system is found alone in some adult Duboisia Leichhardtii and possibly in some southern D. myoporoides. It produces tropine and nortropine only, which are esterified with tropic acid, or as in ajooatropine found in belladonna, with atropic acid, and to a small extent with the isoprene acids referred to above. Some tropine or nortropine may occur as such. Scopine, -tropine and dihydroxytropane are absent. [Pg.814]

After determination of the seasonal variation in alkaloidal content of the leaves, stems and roots of belladonna and the production of evidence that there is a considerable movement of alkaloid upwards from root to leaves and a small transport in the opposite direction, Cromwell found that of a laige number of amines injected, with or without glucose, into... [Pg.814]

Te ifels-dreck, m. asafetida. -kirsche, /. belladonna. -wurz,/. aconite Aconitumnapellus). [Pg.444]

Tokaier, Tokaierwein, m. Tokay (wine). Tolerierung,/. (Tech.) tolerance, toll, a. mad crazy, fiirious, nonsensical. ToU-beere, -kirgche, /. belladonna, -kraut, n. [Pg.447]

The house drink, the Belladonna, which was named for Ms. Arpaia, was unavailable because the kitchen had not sent out the ginger-orange puree required. And the Blue Moon, based on a fresh blueberry puree, which is another of the chef s touches meant to distinguish the cocktails, was being served with a commercial substitute and garnished with a raspberry. [Pg.167]

Alkaloids are heterocyclic basic compounds and widespread in plants. Many of them have specific targets in organisms. For example, the alkaloids atropine and scopolamine of Belladonna are specific antagonists at muscarinic receptors. [Pg.53]

Bellacane Elixir—atropine, scopolamine HBr, hyoseyamine HBr or sulfate, phenobarbital, alcohol, tartrazine Bellacane SR Tablets—1-alkaloids of belladonna, phenobarbital, ergotamine tartrate Bellergal-S Tablets—1-alkaloids of belladonna, phenobarbital, ergotamine tartrate Butibel Elixir—belladonna extract, butabarbital sodium, alcohol, sucrose, saccharin Butibel Tablets—belladonna extract, butabarbitol Chardonna-2 Tablets—belladonna extract, phenobarbital Donnatal Elixir—atropine, scopolamine HBr, hyoseyamine HBr or sulfate, phenobarbital, alcohol, sucrose, saccharin... [Pg.682]

Alkaloids range from the belladonna alkaloids, such as atropine and scopalomine—which are used as poisons, cold remedies, and truth serums —to dextromethorphan, a cough suppressant (anti-tussive). But the most widely known alkaloids are the opiates, such as morphine, heroin, fentanyl, oxycodone, and methadone. These act on... [Pg.178]

By extraction of Solanacean drugs, especially Atropa belladonna, Hyoscyamus niger or other species. On careful extraction L-hyoscyamine is obtained first, which can be racemized to atropine by addition of alkali in ethanolic solution. [Pg.152]

Atropine and its ether analog scopolamine (hyoscine) are potent alkaloids that are found as active compounds in a large number of plants around the world (belladonna alkaloids). The deadly nightshades ( European bittersweet, Solanum dulcamara or belladonna, belladonna) were used in the Mid-... [Pg.234]

Fig. 1 Reflectance scan of a chromatogram track of an Atmpa belladonna extract (A) and of a reference track (B) with 200 ng of both atropine (1) and scopolamine (2). Fig. 1 Reflectance scan of a chromatogram track of an Atmpa belladonna extract (A) and of a reference track (B) with 200 ng of both atropine (1) and scopolamine (2).

See other pages where Belladonnae is mentioned: [Pg.54]    [Pg.54]    [Pg.399]    [Pg.12]    [Pg.65]    [Pg.67]    [Pg.67]    [Pg.68]    [Pg.68]    [Pg.69]    [Pg.70]    [Pg.71]    [Pg.105]    [Pg.114]    [Pg.406]    [Pg.799]    [Pg.813]    [Pg.815]    [Pg.815]    [Pg.820]    [Pg.821]    [Pg.447]    [Pg.518]    [Pg.967]    [Pg.231]    [Pg.468]    [Pg.647]    [Pg.248]    [Pg.139]    [Pg.212]    [Pg.235]   


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