The Chemokine Supergene Families of Ligands and Receptors

Just as there are a variety of chemokines, which comprise different family trees, there is also a growing list of isolated and cloned seven-transmembrane G-protein-coupled chemokine receptors (see Chap. 2 for a more detailed discus- 

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Chemokine names are denoted by the new nomenclature system [60] and the common names given in parentheses. This is by no means a complete account for the 60+ members of these different family members. 

A variety of cytokines and chemokines have been identified to be associated with the evolution of various granulomatous responses, including IL-1, IL-2, IL-4, IL-6, IL-12, tumor necrosis factor (TNF), interferon gamma (IFN-y), growth factors, 

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