The Chassis Concept Biotin Prototrophy and Genome Reduction

The Chassis Concept Biotin Prototrophy and Genome Reduction 

Metabolic engineering aims at improving yields, titers, and productivities. The use of inexpensive media components for fermentation without the need to add cost-intense supplements is desirable. Genome reduction is believed to be important for establishing a lean, but versatile production strain as chassis. 

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