Tetrachloro methyl

Hexanoic acid, 4,6,6,6-tetrachloro-3,3-dimethyl-, methyl ester. EINECS 265-005-4 Hexanoic acid, 3,3-dimethyl-4,6,6,6-tetrachloro, methyl esten Hexanoic acid, 4,6,6,6-tetrachloro-3,3-dimethyl-, methyl ester Methyl 4,6,6,6-tetrachloro-3,3-dimethylhexanoate ... 

Bromination in polar solvents usually gives /n j -3,4-dibromo-2-methyl-3-buten-2-ol in nonpolar solvents, with incandescent light, the cis isomer is the principal product (194). Chlorine adds readily up to the tetrachloro stage, but yields are low because of side reactions (195). 

Penicillin V—see Penicillin, phenoxymethyl-, 7, 300 Penicilloate, benzyl-, 7, 303 Penicilloate, D-a-benzyl-a-methyl ester, 7, 303 Penillamine, benzyl-, 7, 303 Penillic acid, benzyl-, 7, 303 Penilloaldehyde, benzyl-, 7, 303 Penilloic acid, benzyl-, 7, 303 Penillonic acid, benzyl-methyl ester, 7, 303 1,2,3,4,6-Pentaazaindene nomenclature, 1, 18 Pentadeca-5,10-dienols synthesis, 1, 428 Pentadienol, tetrachloro-2H-pyran synthesis from, 3, 740 Pentadienonitrile, 5-(l,2-benzoselenazol-3-yl)-X-ray diffraction, 6, 334 Penta-2,4-dienonitrile, 5-(dimethylamino)-2-(2-thienyl)-... 

On reaction of methyl trifluoropyruvate with phosphorus pentachlonde 1,1,2,2 tetrachloro-3,3,3-trifluoro-l-methoxypropane IS obtained [273] Hexafluo-roacetone hydrazone is oxidized to bis(tnfluoromethyl)diazomethane upon tieat-ment with phosphorus pentachlonde [274]... 

Chemical Name 4,5,6,7-Tetrachloro-1,3-dihydro-2-methyl-2-[2-(trimethylammonio)ethyl] 2H-isoindolium dichloride... 

In chlorinations either a substitution or an addition process can occur with the ultimate reaction pathway(s) determined by a combination of factors, which include the reaction conditions, the positions and natures of any substituents present, and the catalyst used. Uncatalyzed chlorination of benzothiadiazole is an exothermic reaction that gives rise to a mixture of isomeric tetrachloro addition products. These are converted in basic medium into 4,7-dichloro-2,1,3-benzothiadiazole (70RCR923). When an iron(III) catalyst is present 4- and 7-chloro substitution becomes the dominant process. Chlorination of a number of 4-substituted 2,1,3-benzothiadiazoles (43) using an oxidative process gave a combination of chlorinated and oxidized products. The 4-hydroxy, 4-amino-, 4-methyl-amino, and 4-acetoxy derivatives of 43 all formed the chloroquinones (44) (40-61% yields). With the 4-aIkoxy substrates both 44 and some 5,7-dichlorinated product were obtained (88CHE96). 

Mizutani and coworkers57a confirmed the presence of polychloro(methylsulfonyl)biphenyls (159-170) as sulfur-containing metabolites of chlorobiphenyls (Cl-BP) in the feces of mice based on both GLC-mass spectrometry and chemical derivatization. In some cases comparison with authentic samples (161 and 162) was also made. When preparing 161 and 162,2,5-dichloro-3-(methylsulfonyl)aniline, 2,5-dichloro-l-iodo-3-(methylsulfonyl)benzene and 2,2, 5,5 -tetrachloro-3,3 -bis(methyl-sulfonyl)biphenyl were also obtained and their four peak El mass spectra reported572. Similar data were given for the corresponding 4-substituted intermediates, which were involved in the preparation of 162. Also 2,4, 5-trichloro-2 -(methylsulfonyl)-biphenyl was prepared and its four peak mass spectra given. Metabolites 163 and 164 were also identified by comparison with the authentic standards. 

The reaction products from 2,4-dichlorophenol were tetrachloro-phenoxyphenols and tetrachlorodihydroxybiphenyls (Figure 5), as determined from their mass spectra and those of their methyl ethers. 4,6-Dichloro-2-(2, 4 -dichlorophenoxy)phenol (V) was the major phenoxy-phenol the mass spectral fragmentation pattern of o-hydroxyphenol ethers is quite characteristic since a hydrogen transfer occurs during the fragmentation (Figure 6). A trace of a trichlorophenoxyphenol also was detected and was formed presumably by the unsensitized reductive loss of chlorine, discussed previously. 

It explodes on impact or friction, as do the tetrachloro- and 9-ethyl-9-methyl analogues. 

Damerud, P.O., I. Brandt, E. Klasson-Wehler, A. Bergman, R. d Argy, L. Denker, and G.O. Sperber. 1986. 3,3, 4,4 -Tetrachloro[14C]-biphenyl in pregnant mice enrichment of phenol and methyl sulfone metabolites in late gestational fetuses. Xenobiotica 16 295-306. 

Sasson and Rempel [97] showed that the system [(PPh3)3RuCl2]/secondary alcohol is suitable for the selective transformation of 1,1,1,3-tetrachloro into 1,1,3-trichloro compounds. Similarly, Blum and coworkers [98, 99] employed [(PPh3)3RuCl2] as well as polystyrene-anchored Rh, Ru and Ir complexes for the hydrogen transfer from alcohols to trihalomethyl compounds, leading to dihalo-methyl derivatives. For example, one of the Cl atoms of 2,2,2-trichloro-l-phenyl-ethanol was displaced by H at 140-160 °C in 2-propanol. The polymer-anchored catalysts proved to be resistant to leaching [99]. 

Another series of complexes able to coordinate reversibly dioxygen is constituted by the derivatives [M(triphos)(catecholate)]+ illustrated in Scheme 4 (M = Co(III), Rh(III), Ir(III) triphos = MeC(CH2PPh2)3 catecholate = 9,10-dihydroxyphenantrene, di-/er/-butyl-catecholate, 3,4, 5,6-tetrachloro-catecholate, 4-methyl-catecholate, ethyl-3,4-dihydroxy-benzoate and 1,2-dihydroxynaphthalene).23... 

An interesting application of the reaction with sulfuryl chloride consisted in the synthesis of a fully chlorinated hexoside.27 Treatment of methyl 2-chloro-2-deoxy-/3-D-galactopyranoside with sulfuryl chloride and pyridine in chloroform, followed by heating of the product with an excess of pyridinium chloride, afforded a tetrachloride, presumably methyl 2,3,4,6-tetrachloro-2,3,4,6-tetradeoxy-/3-D-allopy-ranoside. 

Mg+" reacts with alkyl halides in the gas phase via a range of substrate-dependent pathways Not all halides are reactive—examples of unreactive substrates include methyl chloride, vinyl chloride, trichloro and tetrachloro ethylene. Reaction with ethyl chloride proceeds via an elimination reaction (equation 18) followed by a displacement reaction (equation 19). For larger alkyl halides, such as isopropyl chloride, chloride abstraction also occurs (equation 20). For multiply halogenated substrates such as carbon tetrachloride, oxidative reactions occur (equations 21 and 22), although organometallic... 

Tetrachloro-l-methylpyrrole is fluorinated92 with potassium tetrafluorocobalt-ate(III) at 180°C to give a mixture (ca. 60% yield) of 3,4-dichloro-2,2,5,5-tetrafluoro-l-methyl-2,5-dihydropyrrole (1) and 3,4-dichloro-2,2,5,5-tetrafluoro-l-(fluoromethyl)-2,5-dihydropyr-role (2). 

The exceptionally easy isomerization of 2-methyl-3,4,5,6-tetrachloro-2//-pyrans 144b (R2 = Me) to its 4H isomer 145b at room temperature32 was mentioned in Section III,J. 

Acetyl-2-methyl-2,5,6-trichloro-2//-pyran (122 R = Cl, R1 = Me) and 3,4,5,6-tetrachloro-2-trichloromethyl-2//-pyran (144c) eliminated hydrogen chloride to provide 2-methylene derivatives 582a162 and 582b.188,444... 

Less commonly used solvents include methyl ethyl ketone, b.p. 80° ethylene chloride, b.p. 84° dioxan (diethylene dioxide), b.p. 101° (vapours are toxic) toluene, b.p. 110° pyridine, b.p. 115-5° chlorobenzene, b.p. 132° cellosolve (ethylene glycol monoethvl ether), b.p. 134-5° di- -butyl ether, b.p. 141° s-tetrachloro-... 

Miscellaneous compounds l-(3-Chloroallyl)-3,5,7-triaza-l-azoniaadamantane chloride 2,3,5,6-Tetrachloro-4-(methyl-sulfonyl)pyridine... 

---