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Testosterone decanoate

Oil-soluble derivatives of testosterone itself predate those of its 19-nor congener these agents too are used to administer depot injections so as to provide in effect long-term blood levels of drug. Thus, acylation of testosterone with propionyl chloride in the presence of pyridine yields testosterone propionate (76a)acylation by means of decanoic anhydride yields testosterone decanoate (76b).Finally, reaction of 75 with 3-cyclopentylpropionyl chloride affords testosterone cypionate (76c)This last undergoes hydrolysis unusually slowly because of the presence of two substituents at the 5 position (see Newman s Rule of 6). ... [Pg.172]

Methyltestosterone Testosterone Testosterone Cypionate Testosterone Decanoate Testosterone Propionate... [Pg.435]

Terolidine 2, 56 Tesicam T79 Tesimide 296 Testolactone 160 Testosterone cypionate 1, 172 Testosterone decanoate T, 172 Testosterone propionate 1, 172 Tetrabenazine 350 Tetracaine 1, 110 Tetracycline 1, 212 Tetrahydrocannabinol, A-1, 1, 394... [Pg.277]

Teratogenic effects, 257 Testosterone cypionate, 172 Testosterone decanoate, 172 Testosterone propionate, 172... [Pg.489]

GC unit. Peak identification is as follows 1, benzylalcohol 2, testosterone propionate 3, testosterone isocaproate 4, testosterone phenylpropionate 5, testosterone decanoate 6, oil matrix (b) GC analysis of the transfer (4 pd) from the micro SEC system (c) Direct GC analysis of a standard solution of the steroid esters. Reprinted from Proceedings of the 10th Symposium on Capillary Chromatography, M. Ghys et al, On-line micro size-exclusion chromatography-capillary gas chromatography, 1989, with permission from Wiley-VCH. [Pg.276]

Triglycerides in pharmaceutical formulation including testosterone phenyl propionate, testosterone propionate, testosterone isocaproate, testosterone decanoate Hypersil ODS, 3 pm Acetonitrile-isopropanol-n-hexane (57 38 5) 50 mM ammonium acetate 250 mm x 100 pm i.d. 52... [Pg.396]

Ester hydrolysis does not invariably lead to inactive metabolites, as exemplified by acetylsalicylic acid. The cleavage product, salicylic acid, retains pharmacological activity. In certain cases, drugs are administered in the form of esters in order to facilitate uptake into the body (enalapril-enalaprilat, p.128 testosterone decanoate-testosterone, p. 248) or to reduce irritation of the gastric or Luellmann, Color Atlas of Pharmacology All rights reserved. Usage subject to terms... [Pg.34]

Sustanon (Testosterone Propionate 30 mg, Testosterone Phenylpropionate 60 mg, Testosterone Isocaproate 60mg, and Testosterone Decanoate 100 mg) 250mg/cc... [Pg.38]

Figure 60. Capillary SFC analysis of steroid esters Column 20 m LxO. I mm i.d. 0.1 pm df MeSi temperatnre 130 °C pressure 200 bar CO FID Peaks (1) testosterone propionate. (2) testosterone isocap-roate, (3) testosterone decanoate. (4) testosterone phenylpropionate... Figure 60. Capillary SFC analysis of steroid esters Column 20 m LxO. I mm i.d. 0.1 pm df MeSi temperatnre 130 °C pressure 200 bar CO FID Peaks (1) testosterone propionate. (2) testosterone isocap-roate, (3) testosterone decanoate. (4) testosterone phenylpropionate...
See other pages where Testosterone decanoate is mentioned: [Pg.246]    [Pg.276]    [Pg.1594]    [Pg.145]    [Pg.51]    [Pg.269]    [Pg.221]    [Pg.270]    [Pg.271]    [Pg.70]    [Pg.244]    [Pg.244]    [Pg.245]    [Pg.299]    [Pg.251]    [Pg.251]    [Pg.253]    [Pg.993]    [Pg.994]   
See also in sourсe #XX -- [ Pg.172 ]

See also in sourсe #XX -- [ Pg.172 ]

See also in sourсe #XX -- [ Pg.383 ]



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