3-Tert-butyl-4-hydroxyanisole

BHA 2-tert-butyl-4-hydroxyanisole 3-tert-butyl-4-hydroxyanisole... 

Figure 4. Intrinsic viscosity of polystyrene samples irradiated in benzene solution under various conditions. Polystyrene concentration 7.69x 10-2 M and initiator I concentration 3.12x 10-3 M. vacuum nitrogen saturated air saturated V oxygen saturated 3.12 3 / 3-tert-butyl-4-hydroxyanisole 3.12x 10-3 M 1.4-diazobicyclo(2.2.2)-octane (DABCO).

Dock, L., Cha, Y-N., Jernstrom, B., and Moldeus, P. Effect of 2(3)-tert-butyl-4-hydroxyanisole on benzo(a)pyrene Metabolism and NDA-binding of Benzo(a)pyrene Metabolites in Isolated Mouse Hepatocytes. Chem. Biol. Interact., 41 ... 

Antimutagenic Effects of 2(3)-tert-butyl-4-hydroxyanisole and of antimicrobial agents. Cancer Res. 38 4478-4485, 1978. 

Standard Preparation Dissolve together accurately weighed quantities of USP Reference Standards 3-tert-Butyl-4-hydroxyanisole and 2-tert-Butyl-4-hydroxyanisole to final concentrations of 9 mg/mL and 1 mg/mL, respectively, in sufficient Internal Standard Solution to make 10 mL. 

SYNS ANTRANCINE 12 BHA (FCC) D BUTYL-HYDROXYANISOLE tert-BUTYLHYDROXYANISOLE ten-BUTYI 4-HYDROXYANISOLE 2(3)-tert-BUTYL-4-HYDROXYANISOLE BUTYLOHYDROKSYANIZOL (POLISH) EMBANOX FEMA No. 2183 ... 

Rao, M. S., Lalwani, N. D., Watanabe, T. K., and Reddy, J. K. (1984). Inhibitory effect of antioxidants ethoxyquin and 2(3)-tert-butyl-4-hydroxyanisole on hepatic tumorigenesis in rats fed ciprofibrate, a peroxisome proliferator. Cancer Res 44, 1072-1076. 

Benson, A. M., Cha, Y.-N., Bueding, E., Heine, H. S., and Talalay, P., Elevation of extrahepatic glutathione S-transferase and epoxide hydratase activities by 2(3)-tert-butyl-4-hydroxyanisole. Cancer Res. 39, 2971-2977 (1979). 

During the course of screening antioxidants from plants, Baek et al. isolated a neolignan from the bark of M. officinalis [37]. A biphenyl compound, 5, 5 -di-2-propenyl-2-hydroxy-3, 2, 3 -trimethoxy-l-l -biphenyl (15), was found to have antioxidant activity similar to commercial synthetic antioxidants 2, 6-di-ter/-butyl-4-methylphenol (BHT) or 3-tert-butyl-4-hydroxyanisole (BHA). Antioxidants are compounds that inactivate free radicals in the body. Free radicals can cause cancer since it can promote the growth of cells by initiating spontaneous mitosis. Furthermore, phenolic antioxidants in wine, especially resveratrol (16), have demonstrated the ability to inhibit human low density lipid (LDL) oxidation in vitro [38]. Frankel mentions other studies suggesting... 

Butylated hydioxyanisole (BHA) (Figure 9.21) is a mixture of two isomeric organic compounds, 2-tert-butyl-4-hydroxyanisole and 3-tert-butyl-4-hydroxyanisole. The conjugated aromatic ring of BHA is able to act as a free radical scavenger, and thus further free radical reactions are prevented. 

The degradation rate is decreased if a radical scavenger is added to the solution. Figure 4 shows the effect of 3-tert-butyl-hydroxyanisol. This scavenger reacts with both benzoyl radicals and polymer radicals thus reducing the degradation rate. The rate of degradation is also decreased by addition of... 

Tert-butyl hydroxyanisole (BHA), tert-butyl hydroxytoluene (BHT), tert-butyl hydroquinone (TBHQ) and propyl gallate (PG) are the most common synthetic phenolic... 

Butylated Hydroxyanisole. 2- and 3-/ i -Butyl-4-methoxyphenol (butylated hydroxyanisole (BHA)) is prepared from 4-methoxyphenol and tert-huty alcohol over siUca or alumina at 150°C or from hydroquinone and tert-huty alcohol or isobutene, using an acid catalyst and then methylating. It is widely used in all types of foods such as butter, lard, and other fats, meats, cereals, baked goods, candies, and beer as an antioxidant (see Antioxidants Eood additives). Its antioxidant properties are not lost during cooking so that flour, fats, and other BHA-stabiLized ingredients may be used to produce stabilized products. 

Antioxidants are not important only to the health conscious food manufacturers also rely on these chemicals to maintain the shelf life of their products. Synthetic antioxidants such as butylated hydroxyanisole, butylated hydroxytoluene, propyl gallate and tert-butyl hydroquinone were widely used in food processing to control oxidation and maintain food quality. However, as these synthetic antioxidants are suspected to be carcinogenic they now have restricted use in food (Madahavi and Salunkhe, 1995). Therefore, natural antioxidant sources, especially of plant origin, are of great interest to the food industry. 

BHT, butylated hydroxytoluene BHA, butylated hydroxyanisole EDTA, ethylenediaminetetraacetic acid MeOH, methanol EtOH, ethanol 2-PrOH, 2-propanol BuOH, butanol MeCN, acetonitrile CHC13, chloroform CH2C12, dichloromethane (methylene chloride) THF, tetrahydrofuran DMF, dimethylformamide DMSO, dimethylsulfoxide MTBE, methyl tert-butyl ether. 

T Stijve. Gas chromatographic determination of butylated hydroxytoluene (BHT), butylated hydroxyanisole (BHA) and tert-butylhydroquinone (TBHQ) in milk products. Deutsch Lebensm Rund-sch 79 108-111, 1983. 

Ratio = blend ratio soybean oil fatty acid methyl esters (SME) in low-sulfur (<500ppm) No. 2 petrodiesel (LSD) where BO is 0% SME and B20 contains 20 vol% SME BHA = butylated hydroxyanisole BHT = butylated hydroxytoluene TBHQ = tert-butylhydroquinone. 

Figure 2-18 Structure of Propyl Gallate (PG), Butylated Hydroxyanisole (BHA), Butylated Hydroxy Toluene (BHT), and Tert-Butyl Hydroquinone (TBHQ)...

All meat samples contained 2Z NaCl and 1.5Z sucrose. The additives were sodium ascorbate SA, sodium tripolyphosphate STPP, butylated hydroxyanisole BHA, tert-butylhydroquinone TBHQ, and sodium nitrite, NaN02. 

C11H1405 genipin 6902-77-8 25.00 1.1972 2 22448 C11H1602 tert-butyl-4-hydroxyanisole 25013-16-5 24.83 1.0121 2... 

Antioxidants are used widely in fats and oils products to delay oxidative processes. Synthetic antioxidants, namely, butylated hydroxyanisole (BHA), butylated hydro-xytoluene (BHT), tert-butyUiydroquinone (TBHQ), and propyl gallate (PG), are permitted antioxidants that are frequently used in products. Their presence and concentration may be determined with HPLC and GC methods. Meanwhile, metal chelators such as citric acid may be determined by HPLC analysis. 

Although alkyl- and aryllithium reagents usually attack the carbonyl group of a, j3-unsaturated carbonyl compounds (1, 2-addition), conjugate addition (1, 4-addition) is observed with very hindered esters where approach to the carbonyl group is impeded, as in 2,6-di-terr-butyl-4-methylphenyl esters (butylated hydroxytoluene, BHT esters) and 2,6-di-tert-butyl-4-methoxyphenyl esters (butylated hydroxyanisole BHA esters). ... 

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