Temperature Differential Scanning Calorimetry MTDSC

MODULATED TEMPERATURE DIFFERENTIAL SCANNING CALORIMETRY (MTDSC) 

As mentioned above, an MTDSC experiment usually involves the application of a sinusoidal perturbation to the linear heating program of a conven- 

An MTDSC experiment can not only generate the total heat flow similar to the heat flow obtained in conventional DSC but also separate the total heat flow into its reversing and nonreversing components. The total heat flow is the sum of the thermal events and is generally equivalent to the heat flow seen in conventional DSC. The reversing heat flow is the heat capacity component (plus other terms in some cases see text below) of the total heat flow Cp dT/dt as noted in Eq. (2.91)]. 

Another benefit of MTDSC is the increased sensitivity observed in the reversing heat flow because of decreased noise level. This is in part due to smoothing, better baseline linearity, and separation of some of the noise separated into the nonreversing signal. 

Unlike conventional DSC where the heat flow is directly related to the temperature difference between the sample and reference signals, the MDSC operational signals are calculated from the modulated signals.The total heat flow is calculated as the average value of the modulated heat flow signal. 

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Thermoanalytical techniques have had a major application in the understanding of transitions in the skin and of drug penetration of the skin. The application of thermoanalytical techniques to prosthetics and implants is also discussed, as are recent DSC investigations of the oesophagus that provided the information on thermal stability required for successful stent implantation. The use of thermoanalytical techniques such as modulated temperature differential scanning calorimetry (MTDSC) has been be used to characterise polymeric material in order to determine whether there are interactions with drug substances to control and predict drug delivery. 

Modulated temperature differential scanning calorimetry (MTDSC, also called temperature modulated DSC or TMDSC) is an extension of conventional DSC in which a modulated temperature input signal is used This modern technique has proven to be very beneficial for the thermal characterisation of many materials, especially polymers [1-5]. 

Reports on the detailed thermal behaviour of PEEK/HAp composites [as well as other polymer/HAp (nano)composites] are scarce in the literature. Advanced thermal analysis methods, e.g., modulated temperature differential scanning calorimetry (MTDSC) or hyphenated thermoanalytical methods such as thermogravimetry coupled with Fourier transform infrared spectroscopy (TG-FTIR) or mass spectrometry... 

Modulated (temperature) differential scanning calorimetry (MTDSC or MDSC) is used to simultaneously study the evolution of heat flow and heat capacity for the isothermal and non-isothermal reactions of polymer systems. An... 

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