TB Alliance

1 Mallard, A. (2012) FDA drug approvals. Nature Reviews Drug Discovery, 2013, 12, 87-90. 

2 Williams, M. (2011) Productivity shortfalls in drug discovery contributions from the preclinical sciences The Journal of Pharmacology and Experimental Therapeutics, 336, 3-8. 

3 Khanna, I. (2012) Drug discovery in pharmaceutical industry productivity 

Pammolli, F Magazzini, L., and Riccaboni, M. (2011) The productivity crisis in pharmaceutical R D. Nature 

6 Morgan, P., Van Der Graaf, P.H., Arrowsmith, J. et al. (2012) Can the flow of medicines be improved Fundamental pharmacokinetic and pharmacological principles toward improving phase II survival. Drug Discovery Today, 17, 419-424. 

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Grabowki, H., J. Dimasi, and R. Hansen. 2004. Assessing Claims about the Cost of New Drug Development A Critique of the Public Citizen and TB Alliance, 1-20. Tufts Center for the Study of Drug Development. Available at http //csdd.tufts.edu/ documents/www/Doc 231 45 735. pdf [Accessed May 10, 2005]. 

For its part, the TB Alliance interviewed outside research organizations that Big Pharma might hire to conduct the early-stage animal trials. Its data on human trials came partly from the experience of staffers who used to work in the industry and partly from government institutions that run trials in the developing world. But the group s 76 million-... 

Figure 11.8 TBA-354 and PA-824, currently evaluated by TB alliance In precllnical and phase lla-b development, respectively. The archetypal nitroimidazole antibiotic metronidazole is shown for comparison.

Tuberculosis and the Global Alliance for Tuberculosis Drug Development (TB Alliance) 729... 

TB Alliance (Global Alliance for TB Drug Development) is a not-for-profit organization dedicated to the discovery and development of better, faster acting, and affordable tuberculosis drugs/regimens. It was founded in 2000 with main offices in New York and Pretoria. We are a product development partnership venture that involves collaboration with academic laboratories and major pharmaceutical companies in order to harness the power of global innovation, expertise, and... 

Glohal Alliance for TB Drug Development. 2001. Economics of TB Drug Development. New York Glohal AUiance for TB Drug Development. Available at http //66.216.124.114/pdf/Economics%20Report%20FuU%20( final). pdf. 

Ridiculous, consumer groups retorted, citing a study by The Global Alliance for TB Drug Development that claims... 

Foundation for Innovative New Diagnostics http //www.finddiagnostics.org Global Alliance for TB Drug Development (www.tballiance.org)... 

F-836 Nuermberger, E. Johns hopkins University, Baltimore F-837 Severynse-Stevens, D. RTI Ind., Research Triangle Park, NC F-838 Cooper, C.B. Global Alliance for TB Drug Development, NY. 

The most recent specific tuberculosis drug, rifampicin, was introduced more than 40 years ago. The challenges posed by the HTV epidemic and drug resistance over the past two decades have finally prompted a search for new tuberculosis drugs. Initiatives such as the Global Alliance for New TB Drug Development have ensured that efforts are now in place to develop new agents with... 

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