Tailor-made compounds

A rhodium complex with chiral phosphane ligand was also intercalated into sodium hectorite by cation exchange (Sento et al. ). The intercalated compound was characterized by FTIR, XRD, and TEM and the basal spacing of the compound was estimated to be 2.29 nm. This novel het-erogenized eatalyst exhibited a characteristic chiral as well as size recognition of the substrate molecule (like the "Tailor-made compounds" method used earlier by Balandin in the hydrogenation of tripticene derivatives over Ni) and was used in enantioselective hydrogenation of the itaconates (methylene-succinic acid esters). 

Curti, R. Colombo, U. Chromatography of stereoisomers with tailor made compounds. J. Am. Chem. Soc. 1952, 74, 3961. 

Although they have not yet been industrially applied, SLMs are of great interest both for potential technological applications (in hollow fibers), and for basic research (in flat sheet SLMs) to determine the transport mechanisms. Because they require only small amounts of organic solutions, SLMs allow the study of very sophisticated tailor-made compounds. Unfortunately, one of their major drawbacks is their great instability. This instability is caused by the disfavourable volume ratio between the aqueous solutions and the organic membrane, which leads to substantial partitioning of the diluent and/or the carrier in the aqueous solutions [10]. 

If it is known that a drug must bind to a particular spot on a particular protein or nucleotide, then a drug can be tailor-made to bind at that site. This is often modeled computationally using any of several different techniques. Traditionally, the primary way of determining what compounds would be tested computationally was provided by the researcher s understanding of molecular interactions. A second method is the brute force testing of large numbers of compounds from a database of available structures. 

Gorriu, R., Jutzi, P., Eds. Tailor-made Silicon-Oxygen Compounds From Molecules to Materials-, Vieweg Braunschweig, 1996. 

While the consideration of nonflammability and SEI stability favors a high concentration of these organophosphorus compounds in electrolytes, the capacity utilization, rate capabilities, and low-temperature operation require that they be used at minimal concentrations. A compromise would be reached between 15 and 20% TFP or BMP in a binary 1.0 M LiPFe in EC/EMC (1 1) system or at higher than 30% in a ternary 1.0 M LiPFe in PC/EC/EMC (1 1 3) system. Such electrolytes are completely or at least nearly nonflammable. To further alleviate the above tradeoff, Xu et al. suggested that new cosolvents of higher flame retarding ability should be tailor-made. 

So far comparisons of isoelectronic systems of types A, B and C are restricted to few examples, becau especially in type B the kinetic instability of the neutral radicals (SEM) becomes so pronounced that the level RED very often caimot be generated. This low persistency of B may be due to the fact that the odd electron is no longer distributed symmetrically over the molecule. In some cases dimeric products have been identified There are, however, tailor made radicals Rsem. -g-55, which exist as highly coloured, destillable compounds Nonetheless, from the... 

Modern technology has been quite successful in developing tailor-made chemicals to cope with specific problems. However, this effort has also introduced some additional problems since manufacturing and handling experience is frequently inadequate to properly answer questions of hazard. Some way is needed to distinguish hazardous from nonhazardous chemicals, and to establish a measure of the extent of hazard As technology solves the questions it encounters, new compositions of matter are formulated. These formulations are compounded of two or more chemicals, each of which may present no special hazard but, once mixed, may... 

Analysis of supramolecular structures in ionic liquids Supramolecular assemblies are the molecular base for some of the unique properties of ILs. Therefore, the knowledge of the nature, type, and strength of these structures [23] is a prerequisite for a deeper understanding of ILs as well as for the tailor-made design of new compounds. The most important noncovalent interactions responsible for the formation of such a structure are C-H hydrogen bonds [25]. Other interactions encompass the formation of clusters by ion pairing, which can be found, for example, in chloroaluminates [12]. 

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