Tacca

Starch is one of the most abimdant plant polysaccharides and is a major source of carbohydrates and energy in the human diet (Zobel and Stephen, 1995). Starch is the most widely used hydrocolloid in the food industry (Wanous, 2004), and is also a widely used industrial substrate polymer. Total annual world production of starch is approximately 60 million MT and it is predicted to increase by additional approximately 10 million MT by 2010 (FAO, 2006b LMC International, 2002 S. K. Patil and Associates, 2007). Com/maize Zea mays L.), cassava (also known as tapioca—Manihot escu-lenta Crantn.), sweet potato Ipomoea batatas L.), wheat Triticum aestivum L.), and potato Solanum tuberosum L.) are the major sources of starch, while rice Oryza sativa L.), barley Hordeum vulgare L.), sago Cycas spp.), arrowroot Tacca leontopetaloides (L.) Kimtze), buckwheat Fagopyrum esculentum Moench), etc. contribute in lesser amounts to total global production. 

Del Tacca M. Prospects for personalized immunosuppression pharmacologic tools - a review. Transplant Proc 2004 36(3) 687-9. 

A few species of the genus have been reported to give positive tests for alkaloids, but three species tested in this study were negative Tacca chanlrieri, T. leontopetalnides, T. pinnatifida. 

Innocenti, F., R. Danesi, A. D. Paolo, C. Agen, D. Nardini, G. Bocci, and M. D. Tacca. 1995. Plasma and tissue disposition of paclitaxel after intraperitoneal administration in rrEteeg Metab. Dispos23 ... 

Malizia T, Batoni G, Ghelardi E, Baschiera F, Graziani F, Blandizzi C, Gabriele M, Campa M, Del Tacca M, Senesi S. Interaction between piroxicam and azithromycin during distribution to human periodontal tissues. J Periodontol 2001 72(9) 1151-6. 

Falcone A, Antonuzzo A, Danes R, Allegrini G, Monica L, Planner E, Masi G, Ricci S, Del Tacca M, Conte P. Suramin in combination with weekly epirubicin for patients with advanced hormone-refractory prostate carcinoma. Cancer 1999 86(3) 470-6. 

Giovannetti, E., Del Tacca, M., Mey, V., Eunel, N., Nannizzi. S., Ricci, S., Orlandini, C, Boggi, U., Campani, D, Del Chiaro, M, lannopollo, M., Bevilacqua, G, Mosca, F., and Danesi, R. (2006) Transcription analysis of human equilibrative nudeoside transporter-1 predicts siuvival in pancreas cancer patients treated with gemcitabine. Cancer Research, 66 (7), 3928-3935. 

Yokosuka A, Mimaki Y, Sashida Y (2002) Steroidal and Pregnane Glycosides from the Rhizomes of Tacca chantrieri. J Nat Prod 65 1293... 

Danesi R, Irmocenti F, FogU S, Gennari A, Baldini E, Di Paolo A, Salvador B, Bocci G, Conte PF, Del Tacca M Pharmacokinetics and pharmacodynamics of combination chemotherapy witii paclitaxel and epirubicin in breast cancer patients. BrJ Clin Pharmacol (2002) 53,508-18. 

Conte PF, Gennari A, Donati S, Salvador B, Baldini E, Bengala C, Pazzagli I, Orlandini C, Danes R, Fogli S, Del Tacca M. Gemeitabine plus epirubicin plus taxol (GET) in advanced breast cancer a phase II study. Breast Cancer Res Treat (2001) 68, 171-9. 

Fogli S, Danesi R, De Braud F, De Pas T, Curigliano G, Giovannetti G, Del Tacca M. Drug distribution and pharmacokinetic/phaimacodynamic relationship of paclitaxel and gemcital> ine in patients with non-small-cell lung cancer. Ann Oncol (2001) 1 1553-9. 

Falcone A, Di F olo A, Masi G, All ini G, Danes R, Lencioni M, Pinner E, Comis S, Del Tacca M, Conte P. Sequence effect of irinotecan and flucx oumcil tieatnient on phannacol et-ics and toxicity in chemothempy-naive metastatic colorectal cancer patients. J Clin Oncol (2001) 19, 3456-62. 

Allegrini G, Di Paolo A, Cerri E, Cupini S, Amatori F, Masi G, Danesi R, Marcucci L, Bocci G, Del Tacca M, Falcone A. Irinotecan in combination witii thalidomide in patients widi advanced solid tumors a clinical study with pharmacod3mamic and pharmacokinetic evaluation. 

---