Tablets, novel dosage form

Buccal dosage forms can be of the tablet, patch, gel, or ointment type and can be employed for local or systemic delivery. For local deliveiy, conventional dosage forms such as solutions and various types of tablets (immediate release, effervescent, etc.) are more suitable. These forms generally have uncontrolled drug release with subsequent variable absorption and short residence times, and may not provide sufficient bioavailability. Novel dosage forms such as adhesive tablets, patches, gels, and... 

Novel dosage forms such as adhesive tablets, patches, gels, and ointments have been developed primarily... 

There have also been several references to the use of carrageenan in chewable tablets having a confectionary texture.This approach to creating a novel dosage form requires the use of both i-carrageenan and K-carrageenan, to prevent moisture loss and texture changes that occur over time. 

For a very long time, scientists generally underestimated the importance of excipients in pharmaceutical dosage forms. Excipients were cheap ingredients viewed solely as inert supports for medicaments. Today, with modern pharmaceutical excipients on the shelf, development of various novel drug delivery systems, and production with high-speed tablet/capsule machines, excipients are rather more than the sugar in the pill.9,10... 

Hariharan, M. Gupta, V.K. Encore a novel compression-coated tablet dosage form. Proceed. Int. Symp. Control. Rel. Bioact. Mater., San Diego, CA, 2001 Controlled Release Society Minneapolis, MN, 2001 6102. 

UL medicines are medicines under an rmlicensed dosage form obtained after manipulation of the original dosage form (e.g. crush-ing/cutting tablets, extemporaneous preparations, special ). Sometimes the drug itself may have no licence at all (e.g. chemicals used in metabolic diseases, such as betaine to treat homocystinuria, and novel medicines). Imported medicines become rmlicensed in the country into which they are imported. 

In view of the importance of API solubility in the HPLC analysis of pharmaceutical dosage forms, this chapter will examine some of the strategies that may be employed to assure optimum and quantitative recovery of the API during the sample preparation steps prior to HPLC analysis. In addition, emphasis on sample preparation strategies used for tablets and capsules will frequently be referred to and also serve as examples throughout the chapter because tablets and capsules are the most commonly used novel pharmaceutical dosage form delivery platforms. 

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