Tabebuia avellanedae

Pereira, E.M. et al., Tabebuia avellanedae naphthoquinones activity against methi-cillin-resistant staphylococcal strains, cytotoxic activity and in vivo dermal irritability analysis, Ann. Clin. Microbiol. Antimicrob., 22, 5, 2006. 

Oxidation product of polyhydroxyphenolic Gallic acid Haplophragma adenophyllum, Phyllarthron comorense [wood], Tabebuia avellanedae [wood] (Bignoniaceae), Tectona grandis (Verbenaceae) [root]... 

The presumed biosynthetic precursor of 6-methoxymellein, 6-hydroxymellein (10), has also been isolated from carrot roots stored under stress (ref.32). This compound was first isolated from a mutant of Aspergillus terreus (ref.42) and subsequently has been found in the bar)c of Tabebuia avellanedae (ref. 43) and produced by the fungi Pyricularla oryzae (ref. 44) and Ceratocystis minor (ref.45). Recently, the ( + )-6-hydroxymellein isomer has been isolated from the flowers of Cassia siamea (ref.46) and from a fungus of the genus Discula (ref.47). 

Syn Tabebuia avellanedae Lorentz ex Griseb. Tabebuia hep-taphylla (Veil.) Toledo Tecoma impetiginosa Mart, ex DC. 

Queiroz, M.L.S., M.C. Valadares, C.O. Toiello, et al. 2008. Comparative studies of the effects of Tabebuia avellanedae bark extract and (i-lapachone on the hematopoietic response of tumour-bearing mice. /. Ethnopharmacol. 117(2) 228-235. 

In the light of all these findings, it is plausible to assume that some cancer drugs of plant origin such as mistletoe (Viscum album) or the South American lapacho (Tabebuia avellanedae), which are applied in very low concentrations with regard to the active constituents present in the preparations of traditional medicine, exert their antitumor activities by a total or partial immune or apoptosis inducing mechanism of action. 

Burnett AR, Thomson RH 1967 Naturally occurring quinones. Part X. The quinonoid constituents of Tabebuia avellanedae (Bignoniaceae). J Chem Soc C. 2100-2104... 

Roots of Ekmanianthe longiflora [78] roots of Zeyhera montana [37] Kigelia pinnata [93] roots of Tectona grandis (Verbenaceae) [46] roots and leaves of Newbouldia laevis [94-95] wood of Tabebuia palmeri [96] wood of T. chrysotricha [97] wood of T. serratifolia [98] heartwood of Tecomella undulatum [99] heartwood of Dolichandrone crispa [100] heartwood of T. avellanedae [101]. 

Bignoniaceae (Tabebuia impetiginosa, heptaphylla, avellanedae, pan d arco) Celasteraceae (Maytenus ilicifolia, espinephra santa)... 

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