Syphacia obvelata

Dibenzothiophene, its sulfoxide, and its sulfone are inactive as anthelmintic agents against Syphacia obvelata and Aspiculuvis... 

When administered continuously in the diet of experimental animals, it brought about the removal of the pinworm Syphacia obvelata in mic Ascaridia galli in chickens, and Tox-ocara canis, Ancylostoma c aninum, and... 

Some members of the orthosomycins, a group of compounds known for their antibiotic activity, showed activity against intestinal nematodes [429], The nucleoside peptide aspiculamycin (250), isolated from Strepto-myces toyocaensis, at 50 mg/kg, completely eliminated Aspicularis tetra-ptera and Syphacia obvelata (pinworm) from the intestinal tract of infected mice [430]. The related compound (251) has been claimed to show nematocidal activity towards B. lignicolus [431]. Anthelmycin (252) (hikizimycin) has been found to be effective against pinworms, round-worms and whipworms [432]. 

Nematodirus sp., 37°C Neoaplectana glaseri, 30 C Nippostrongylus muris, 37°C Ostertagia circumcincta, 38°C Setaria equinum, 38°C Strongylus equines, 38°C Syphacia obvelata, 38°C... 

The antiparasitic properties of essential oils from A. absinthium, Artemisia annua, and Artemisia scoparia were tested on intestinal parasites Hymenolepis nana, Lamblia intestinalis, Syphacia obvelata, and Trichocephalus muris Trichuris muris). Infested white mice were injected with 0.01 mL/g of the essential oils (6%) twice a day for 3 days. The effectiveness of the essential oils was observed in 70% 90% of the tested animals (Chobanov et al., 2004). 

Berberine chloride shows anthelmintic activity and is able to eliminate Syphacia obvelata from mice. A series of synthetic 8-substituted tetrahydroprotoberberines has demonstrated both antifungal and antiarrhythmicactivity. Berberine sulfate and tetrahydropalmatine inhibit the respiratory chain by interfering with the action of NADH oxidase." ... 

Enterobiasis - Activity against pinworms in mice has been reported for certain series of compounds which have not reached clinical trial. Some derivatives of 9-aminoacridine and related benz [c] acridine and benzo Oo] C Sj naphthyridine had activity against Syphacia obvelata as As-piculuris tetraptera in mice. Three of 10 arylsydnones had activity against S. obvelata, somewhat lower than that of piperazine. 

The antibiotic paromomycin (sulfate) cured 12 of 13 patients infected with the cestode Hymenolepis nana.i 9 Cephamycin C (A-11884), an antibiotic isolated from Streptomyces limanii is active against Aspicularis tetraptera, Syphacia oBvelata and Ascaris lumbricoides.iso... 

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