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Synthesis and Single Molecule Nanomechanical Studies of Peptidomimetic 3-Sheet Modular Polymers

Synthesis and Single Molecule Nanomechanical Studies of Peptidomimetic fi-Sheet Modular Polymers [Pg.244]

Chart 10.2 Different folding topologies in the first-generation UPy modular polymer. [Pg.245]

Chart 10.3 Peptidomimetic /8-sheet modules with varying numbers of H bonding sites. [Pg.248]

3-D Network Polymers Containing Biomimetic Reversibly Unfolding Crosslinkers for Advanced Mechanicai Properties [Pg.248]

Based on our and other s single molecule nanomechanical studies (Guan et al. 2004 Roland and Guan 2004 Zou et al. 2005), the UPy module still has significantly higher mechanical stability than other peptidomimetic /3-sheets that we investigated. This could be partially attributed to the compact stmcture of UPy that favors high [Pg.249]




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Modular

Modular synthesis

Modularity

Modularization

Molecule synthesis

Nanomechanics

Peptidomimetics

Peptidomimetics synthesis

Polymer single

Polymers sheeting

Polymers studied

Sheet polymers

Sheets synthesis 34-39

Single synthesis

Single-molecule studies

Study of Polymers

Synthesis of polymers

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