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Sulfonic acid amides anhydride

BMB reduces only specific functional groups. In tetrahydrofiirane at 0° it reduces aldehydes and ketones to alcohols, -y-valerolactone (11) to y-hydroxyvaleraldehyde (12), and N,N-dimethylamides to aldehydes. Under the same conditions it does not reduce carboxylic acids, sulfonic acids, amides, esters, acid chlorides, anhydrides, or sulfones. The failure of the carboxyl group to react makes possible the conversion... [Pg.32]

A-Phosphorylated imidazoles and benzimidazoles can be made by direct phosphorylation by halides, esters, amides, amidoesters, isocyanates, and thiocyanates of phosphorus-containing acids, or from reaction of phosphonic or phosphinic imidazolides with a sulfonic acid or anhydride <82CB1636>. Stable charge transfer complexes are produced when a 1 1 or 1 2 ratio of imidazole (or benzimidazole) and sulfur trioxide are refluxed in ether, dioxane, THE, or 1,2-dichloroethane. These complexes are stable on storage in the absence of water and have sharp melting points. Indeed, the benzimidazole SO3 complex must be boiled for five hours in water to decompose it. On fusion, the complexes form the C-sulfonic acids (see Section 3.02.5.3.3) <87CHE1084>. Sulfonyl chlorides readily A-sulfonate imidazoles <94JMC332>. [Pg.118]

Conversion of the carboxylic acid to the diethyl amide interestingly leads to an agent that exhibits the properties of a respiratory stimulant. One synthesis of this agent starts with the preparation of the mixed anhydride of nicotinic and benzene-sulfonic acid (4). An exchange reaction between the anhydride and diethyl benzenesulfonamide affords nikethemide (5). ... [Pg.253]

Because C-H bonds are usually less reactive towards dioxirane oxidation than heteroatoms and C-C multiple bonds, it is instructive to give a few general guidelines on the compatibility of functional groups within the substrate to be submitted to oxidative C-H insertion Substances with low-valent heteroatoms (N, P, S, Se, I, etc.), C-C multiple bonds, and C=X groups (where X is a N or S heteroatom) are normally not suitable for C-H insertions, because these functionalities react preferably. Even heteroarenes are more susceptible to dioxirane oxidation than C-H bonds, whereas electron-rich and polycyclic arenes are only moderately tolerant, but electron-poor arenes usually resist oxidation by dioxiranes. N-oxides and N-oxyl radicals are not compatible because they catalyze the decomposition of the dioxirane. Oxygen insertion into Si-H bonds by dioxirane is more facile than into C-H bonds and, therefore, silanes are not compatible. Substance classes normally resistant towards dioxirane oxidation include the carboxylic acids and their derivatives (anhydrides, esters, amides, and nitriles), sulfonic acids and their de-... [Pg.513]

NITRILES Chlorosulfonylisocyanate. Dimethylaluminum amide. Hydroxyl-amine. Hydroxylamine-O-sulfonic acid. Selenium dioxide. Triethoxydiiodophos-phorane. Trifluoroacetic anhydride-Pyridine. Trimethylamine-Sulfur dioxide. [Pg.574]

Both carboxylic and sulfonic acids can be converted into esters, anhydrides and amides. [Pg.66]

Sn[N(TMS)2l2, A, A -carbonyldiimidazole (110, p. 1418), which behaves as in reaction 16-63, POCl3, °" TiCl4, ° molecular sieves,Lawesson s reagent (p. 1278), ° and (MeO)2POCl. ° Certain dicarboxylic acids form amides simply on treatment with primary aromatic amines. In these cases, the cyclic anhydride is an intermediate and is the species actually attacked by the amine. Carboxylic acids can also be converted to amides by heating with amides of carboxylic acids (exchange),sulfonic acids, or phosphoric acids, for example, ... [Pg.1432]

Activation with sulfonic acid chlorides is more general, rendering amides with the possible participation of symmetric anhydrides after disproportionation. This method has also found use in the synthesis of modem 3-lactam antibiotics. However, in peptide chemistry this activation method leads to unwanted side reactions, like formation of nitriles in the cases of glutamine and asparagine, and racemization. In a convenient one-pot procedure, the carboxylic acids are activated by sulfonyl chlorides under solid-liquid phase transfer conditions using solid potassium carbonate as base and a lipophilic ammonium salt as catalyst. ... [Pg.388]

Dehydration Alumina (see also Dihydropyrane, preparation). Boric acid. Boron triSuoride. N-Bromoacetamide-Pyridine-SOj. Dicyclohexylcarbodiimide. Diketene. Dimethylform-amide-Thionyl chloride. Dimethyl sulfoxide. Ethylene chlorophosphite. Florisil. Girard s reagent. Hydrobromic acid. Iodine. Mesyl chloride-Sulfur dioxide. Methyl chlorosulfite. Methylketene diethylacetal. Naphthalene-d-sulfonic acid. Oxalic acid. Phenyl isocyanate. Phosgene. Phosphorus pentoxide. Phosphoryl chloride. Phthalic anhydride. Potassium bisulfate. Pyridine. Thionyi chloride. Thoria. p-Toluenesulfonic acid. p-Toluenesulfonyl chloride. Triphenylphosphine dibromide. [Pg.1387]

ANILINE-4-SULFONIC ACID (121-57-3) Decomposes on contact with strong acids, forming sulfur trioxide. Aqueous solution is acidic violent reaction with strong bases. Incompatible with alkylene oxides, aliphatic amines, alkanolamines, amides, ammonia, epichlorohydrin, organic anhydrides, isocyanates, oxidizers, vinyl acetate. [Pg.117]

In addition to ion formation the sulfonic acid group may form other derivatives, such as sulfonyl chlorides, amides, anhydrides, etc. The literature referring to these derivatives is much less extensive and their importance is rather limited. These will be referred to in Section IV. [Pg.880]

The amino amides 195 were obtained from isatoic or 6-iodoisatoic anhydrides and the esters of amino acids. They were converted by the action of aromatic aldehydes or acetone into derivatives of dihydro-4-quinazolone 196 (ethanol, piperidine, boiling for 1 h, or cone, hydrochloric acid, boiling for 6 h [117] toluene, toluene sulfonic acid, boiling for 0.5 h, [118]). [Pg.31]

This chapter will discuss methods for the preparation of esters, acid chlorides, anhydrides, and amides from carboxylic acids, based on acyl substitution reactions. Acyl substitution reactions of carboxylic acid derivatives will include hydrolysis, interconversion of one acid derivative into another, and reactions with strong nucleophiles such as organometallic reagents. In addition, the chemistry of dicarboxylic acid derivatives will be discussed, as well as cyclic esters, amides, and anhydrides. Sulfonic acid derivatives will be introduced as well as sulfate esters and phosphate esters. Finally, nitriles will be shown to be acid derivatives by virtue of their reactivity. [Pg.944]

In summary, the reactivity of various functional groups toward Li 9-BBNH is classified into four broad categories [18] (1) rapid- or fast-reduction aldehyde, ketone, ester, lactone, acylchloride, acid anhydride, epoxide, disulfide, -alkyli-odide, and tosylate (2) slow-reduction tertiary amide, alkylbromide, and aromatic nitrile (3) sluggish-reduction carboxylic acid, aliphatic nitrile, primary amide, nitro and azoxy compounds, and secondary alkylbromide and tosylate (4) inert olefin, oxime, alkylchloride, sulfoxide, azo-compound, sulfide, sulfone, and sulfonic acid. [Pg.414]

Radical substitution of the hydrogen from the methyl groups PHj OH,X Kl( -HY CH3 X CH, hc=ch X-Y = Br-Br,C1-C1 (12) RS0.-C1 (13) I 1 ( ) Halogenation, sulfonation, binding of maleric anhydride group, unsaturated carboxyl acids, amides, imides, esters, epoxides, amines, alcohol can be used Product of (12) is precursor for PCMs, that of (13) for direct PCMs. [Pg.47]

Strong pyridine anhydrides sulfoxides tertiary amines aliphatic or aromatic hydroxyl carboxylic acid urea urethane sulfonic acids primary and secondary amines amide phosphonic acids... [Pg.38]


See other pages where Sulfonic acid amides anhydride is mentioned: [Pg.560]    [Pg.134]    [Pg.83]    [Pg.494]    [Pg.509]    [Pg.6]    [Pg.1160]    [Pg.358]    [Pg.83]    [Pg.405]    [Pg.420]    [Pg.3083]    [Pg.391]    [Pg.124]    [Pg.1424]    [Pg.391]    [Pg.119]    [Pg.134]    [Pg.87]    [Pg.155]    [Pg.631]    [Pg.1114]    [Pg.1399]    [Pg.1399]    [Pg.1711]    [Pg.135]    [Pg.611]    [Pg.598]   


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Amide sulfon

Amides Anhydrides

Amides sulfonated

Sulfonic acid amides

Sulfonic acid amides sulfonates

Sulfonic acid amides sulfones

Sulfonic anhydrides

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