Nitrile, aliphatic

Aldehydes or Ketones with Other Functional Groups Aldehydes, Ketones with Other Functional Groups Kepone Chlordecone Aliphatic Flydrocarbons Aliphatic Nitriles and Cyanates Acetonitrile Acrylonitrile Aliphatic Nitriles Aliphatic Nitrosamines Aliphatic Nitrosamines A-Nitrosodimethylamine (NDMA)... 

Nitriles. Aliphatic and aromatic amides (carboxamides) are dehydrated by HMPT at 220-240° to give nitriles in good yield. A phosphorodiamidate derivative (a) was. suggested as an intermediate. 

Other nitriles, aliphatic and aromatic, have been investigated as solvents for electrolysis. Butyronitrile has been suggested as the solvent of choice for low-temperature electrochemistry [86], and propionitrile has in some cases been employed, as it is less... 

A notable difference in Red-Al selectivity relative to LAH involves the reduction of nitriles. Aliphatic nitriles do not react with Red-Al. 

Substrate specificity aliphatic nitriles aliphatic nitriles aliphatic and aromatic nitriles... 

Oxidative conversion of aldehydes into nitriles. Aliphatic aldehydes are converted directly into nitriles when treated with excess hydroxylamine-O-sulfonic acid at 25° (60-90% yield). Aromatic aldehydes under the same conditions are converted into oximino derivatives, ArCH=NOS03H, which are converted into nitriles either by decomposition at 65 or by cleavage with sodium hydroxide (yields 80-95%). ... 

Methyl ketones. Nitriles (aliphatic and aromatic) are converted into methyl ketones by reaction with trimethylaluminum in the presence of various catalysts,... 

General. Reduces most groups aldehydes, ketones, acids and acid derivatives, nitriles, aliphatic nitro, halides and propargyl alcohols... 

Monosubst. acetylene Disubst. acetylene C==C=CH2 Allene Nitrile, aliphatic Nitrile, aromatic... 

Reduction of nitriles. This sodium acyloxyborohydride reduces nitriles (aliphatic and aromatic) to primary amines at room temperature in high yield. The reaction appears to be sekclive —COOC2H5, —NOa, and —Cl groups are not reduced. ... 

Takeuchi and coworkers reported an iridium-catalyzed cycloaddition of a,o -diynes and nitriles to give pyridines in 2012 [57]. With [Ir (cod)Cl]2/DPPF or BINAP as the catalytic system, pyridines were formed effectively (Scheme 3.24). A wide range of nitriles (aliphatic and aromatic nitriles) can be applied and reacted smoothly with Q ,a -diynes to give the pyridines. In the case of unsymmetrical diyne bearing two different internal alkyne moieties, high regioselectivity can be achieved which can be explained by the different reactivities of the a-position in iridacyclopentadiene. Terpyridine and quinquepyridine were prepared as well. [Ir(cod)Cl]2/chiral diphosphine catalyst can be applied to enantioselective synthesis. Kinetic resolution of the racemic... 

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