Sulfoacetic acid

A.lkylSulfoacetates. These surfactants are prepared by esterification of sulfoacetic acid or by sulfonation of the alkyl chloroester. They are considered to produce good foaming and are less irritating to the eyes than the alkyl and alkyl ether sulfates (10). 

Trimethylpyrylium perchlorate has been prepared from 2,6-dimethylpyrone and methylmagnesium halides 6 from mesityl oxide and sulfoacetic acid 6 from mesityl oxide (or less satisfactorily from acetone) and a mixture of acetic anhydride and perchloric acid 7 from mesityl oxide, acetyl chloride, and aluminum chloride 8 and from <-butyl chloride, acetyl chloride,... 

SUCCINIMIDE, N-IODO-, 42, 73 Sulf anilic acid, reaction of the diazonium salt with substituted benzyl alcohols to give aldehydes, 44,. 4 Sulfoacetic acid, 44, 102 Sulfonation of pyridine, 43, 97... 

Access to this type of compound is illustrated in Scheme 30 by the preparation of retro-sulfonamide tripeptide Boc-Pro-Leuijt[NH—S02]Gly-NH2(78). The two false termini used are the prochiral gem-diamino analogue of Leu and sulfoacetic acid. Amide to amine conversion according to Hofmann, carried out on the dipeptide Boc-Pro-Leu-NH2 (76) with iodobenzene l,l-bis(trifluoroacetate) gave the gem-diamino derivative 77. Coupling of the resulting gem-diamino derivative with methyl (chlorosulfonyl)acetate, followed by amida-tion of the intermediate methyl ester, afforded the desired pseudopeptide 78J1341 Full experimental details have not yet been reported. 

Two compounds of sulfoacetic acid (H03SCH2C02H) were described by Hahn and Wolf in 1925, but there appears to have been no detailed study since on this ligand, or any other alkylsulfonic acid with Mn11. 

My earlier communication led to comments by Limpricht, most of which I do not feel the need to go into. One part, however, requires discussion, since it concerns important theoretical questions. Limpricht claims that there is no justification for my earlier remark that the view supported by him and v. Uslar leaves unexplained, how, by substitution of S 2 the place of H, the dibasic sulfoacetic acid is formed from monobasic acetic acid. He says (Ann. 105, 182) We cannot quite understand how according to our view the dibasic nature of this sulfoacid remains unexplained in fact, any other basicity would be in complete disagreement with our view. I remain of the opinion that the so-called basicity law does admittedly allow the prediction to a certain... 

Sulfoacetic acid, H03SCH2C00H (1). The acid is prepared in situ from acetic anhydride and cone, sulfuric acid. 

The statement in Vol. 2, 389 that the correct formula for sulfoacetic acid is HOOCCH,SO,OH needs to be elaborated by the further statement that the compound mentioned in I, 1117 is acetyl sulfuric acid. 

Sulfoacetic acid is best prepared by the action of sodium sulfite on sodium chloro-... 

The Liebermann-Burchard test for unsaturated sterols involves addition of sulfoacetic acid to a solution of the sterol in chloroform and is characterized by a brilliant array of colors. ... 

Color reactions Boric acid (hydroxyquinones). Dimethylaminobenzaldehyde (pyrroles). Ferric chloride (enols, phenols). Haloform test. Phenylhydrazine (Porter-Silber reaction). Sulfoacetic acid (Liebermann-Burchard test). Tetranitromethane (unsaturation). Condensation catalysts /3-Alanine. Ammonium acetate (formate). Ammonium nitrate. Benzyltrimethylammonium chloride. Boric acid. Boron trilluoride. Calcium hydride. Cesium fluoride. Glycine. Ion-exchange resins. Lead oxide. Lithium amide. Mercuric cyanide. 3-Methyl-l-ethyl-2-phosphoiene-l-oxlde. 3-Methyl-1-phenyi-3-phoipholene-1-oxide. Oxalic acid. Perchloric acid. Piperidine. Potaiaium r-butoxIde. Potassium fluoride. Potassium... 

N-Sulflnyl-p-toluenesulfonamide, 98 Sulfoacetic acid, 1117-1118 Sulfolane, see Tetramethylene sulfone Sulfomonoperacid, see Caro s acid Sulfones, 988 Sulfonic adds, 952, 1125 Sulfonyl chlorides, 1159 Sulfosalicylic acid, 1118 Sulfoxides, 810, 988... 

Sulfoacetic acid. CH3COOSO.2OH. A solution of the reagent is prepared by drop-wise addition with ice cooling of coned, sulfuric acid to acetic anhydride. The crystalline product was isolated by Stillich. ... 

Hauser and co-workers converted aliphatic ketones into their enol acetates by I caction with ketene in the pre.sence of 0.5% sulfoacetic acid. 

Enamine formation Calcium chloride. Molecular sieves. Morpholine. p-Toluenesulfonic add. Enolacetylation Isopropenylacetate. Perchloric acid. Sulfoacetic acid. p-Toluenesulfonic acid. 

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