Structure paradigm

The zinc-binding site of carbonic anhydrase serves as a structural paradigm for the incorporation of a de novo zinc-binding site in an antibody (Iverson a/., 1990 Roberts cf a/., 1990 Tainer and Roberts, 1990). Because individual antibody light- and heavy-chain libraries can be com-... 

Kostarelos K, Miller AD (2005) Synthetic, self-assembly ABCD nanoparticles a structural paradigm for viable synthetic non-viral vectors. Chem Soc Rev 34 970-994... 

Each of the natural peptides derived from MLCK contains a 16-residue segment that conforms to the structural paradigm derived from the studies of model amphiphilic peptides. When aligned as in Fig. 8, hydrophobic and basic residues tend to occupy invariant positions in their sequences. As illustrated in the helical net diagram (Fig. 9), all three peptides display a potential apolar ridge. This ridge is formed by hydrophobic residues that occur at positions — 3,, -+- 3 over a 10-residue stretch of the chain. This repeat has been found in many helix-helix packings (Chothia, 1984). 

The closo-, nido-, arachno-borane structural paradigm... 

D. L. Griffith, P. C. Keck, T. K. Sampath, D. C. Rueger, and W. D. Carlson. Three dimensional structure of recombinant human osteogenic protein 1 Structural paradigm for the transforming growth factor P superfamily. Free Natl Acad Sci, USA, 93, 878, 1996. 

Modeling of surface reactions has kept pace with the new spectroscopic views of mineral surface structures. Chang et al. (30) and Van Riemsdik and Hiemstra (31) present excellent examples of the incorporation of new surface structure paradigms into computer modeling studies. 

Ghosh, S. et al. (2001) Synthesis of [(Cp Re)2BnHn] n=8-10 metal boride particles that stretch the cluster structure paradigms. Angew. Chem. Int. Ed.,... 

Fig. 1. Hybrid organic-inorganic polymer systems can be devised for all structural paradigms of polymer chemistry including (a) homopolymer, (b) block copolymer, (c) copolymer, (d) graft copolymer, and (e) interpenetrating polymer networks, including, shown as geometrical abstractions, (f) true and (g) semi-interpenetrating versions, where crosslinks are depicted as junctions of horizontal and vertical lines.

Koenigsmaim C, Wong SS (2011) One-dimensional noble metal electrocatalysts a promising structural paradigm for direct methanol fuel cells. Energy Environ Sci 4 1161-1176... 

R 471 J. Pavlicek, D. Kavan, P. Pompach, P. Novak, O. Luksan and K. Bezouska, Lymphocyte Activation Receptors New Structural Paradigms in Group V of C-Type Animal Lectins , Biochem. Soc. Trans., 2004,32,1124... 

Golovchak R., Shpotyuk 0., Koz5nikhin S., Kovalsky A., Miller A. C., and Jain H., Structural paradigm of Se-rich Ge-Se glasses by high-resolution x-ray photoelectron spectroscopy, J. Appl. Phys., 105, 103704-7 (2009). 

The compositional paradigm proved very successful when reinforced by John Dalton s atomic hypothesis. By the middle of the nineteenth century, the definition of a compound by the nature and proportion of its constituents was being challenged by a structural paradigm that took into account the arrangement of atoms in molecules. Nevertheless, structural formulas do not respect the either/or condition any more than the compositional approach, but instead displace it. On this model, it is the physical arrangement of the constituent elements that accounts for the properties of the compound. 

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