Structural Biology and Catalytic Mechanism

In human CatA, the catalytic triad consists of SerlSO, His429, und Asp372 [5]. The catalytically active monomer consists of 32kDa and 20kDa polypeptide chains linked by disulfide bonds with the active site located on the larger chain. In the 54kDa inactive CatA precursor crystallized by Rudenko in 1995, the 

Lead Generation Methods, Strate es, and Case Studies, First EditioiL Edited by Jorg Holenz. 

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