Stroke hostility

The treatment goals for acute intoxication of ethanol, cocaine/amphetamines, and opioids include (1) management of psychological manifestations of intoxication, such as aggression, hostility, or psychosis, and (2) management of medical manifestations of intoxication such as respiratory depression, hyperthermia, hypertension, cardiac arrhythmias, or stroke. 

Stimulants first may cause exhilaration and hyperactivity, dilated pupils, then produce irritability, anxiety, apprehension, and insomnia. Large doses of stimulants can cause repetitive teeth grinding, weight loss, and paranoia. An overdose can result in dizziness, tremors, agitation, panic, hostility, abdominal cramps, chest pains, and palpitations. Extreme overdoses can result in cardiac arrest, stroke, or death. 

Most of the time, the process is slow and insidious. Hypertension and the resultant heart attacks and strokes don t develop overnight. But in our stress-ridden society, anger and hostility can kill suddenly and dramatically. It was a California psychologist who... 

Stem cell-based therapy for cerebral ischemia will be more complicated, because the extensive cell death and massive inflammatory response make these brains a more hostile environment for cell grafts. Various sources of cells have been tested for their ability to reconstruct the forebrain and improve function after transplantation in animal models of stroke (Lindvall and Kokaia, 2004). In most cases, only a few grafted cells could survive. Some recent exciting findings in rodents suggest that stroke can induce an increase in neurogenesis thus, a new therapeutic approach based on self-repair has been brought forth, as discussed in Sect. 13.11.1. 

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