Strategies for design

This chapter describes the four main design strategies for development of inherently safer processes ... 

Smillie, R. J. (1985). Design Strategies for Job Performance Aids. In T. M. Duffy R. Waller (Eds.), Designing Usable Text. New York Academic Press. 

The design strategy for fatty acid synthesis is this ... 

Parang K, Sun G (2004) Design strategies for protein kinase inhibitors. Curr Opin Drag Dicov Devel 7 617-629... 

Honma T. Recent advances in de novo design strategy for practical lead identification. Med Res Rev 2003 23 606-32. 

Design strategies for raw material intensive products. Ideas for reducing environmental impact when the current solution is raw material intensive ... 

Mitchell, T., Showell, G. A. Design strategies for building drug-like chemical libraries. Curr. Opin. Drug Discov. Dev. 2001, 4, 314-318. 

Johansson MK, Cook RM (2003) Intramolecular dimers a new design strategy for fluorescence-quenched probes. Chemistry 9 3466-3471... 

Klabunde, T. and Hessler, G. (2002) Drug design strategies for targeting G protein-coupled receptors. ChemBioChem 3,928-944. 

Thus, the basic design strategy for storing and handling hazardous materials can be summarized as follows, with reference to other parts of this section in parentheses ... 

Table19.1 Structure-Based Design strategy for Improving 5-HT1A/a- selectivity oflead compound 1.

Table 19.3 Structure-based design strategy for reducing hERG blocking of compound 15.

Hapten design strategy for generation of an active site with a suitable catalytic residue has been further demonstrated. Thus, catalytic antibody 43D4-3D12, which was generated against the tertiary amine (61), has been found to catalyse the selective... 

Rose, S. and Stevens, A. Computational design strategies for combinatorial... 

This rest of this section will deal with design, both in the broader and narrower sense, although it will not be possible to give a detailed account of individual design strategies, for which the reader is referred to other excellent texts (see recommended reading list). 

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